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Neupro and Urticaria - a phase IV clinical study of FDA data

Summary:

Urticaria is reported as a side effect among people who take Neupro (rotigotine), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Xyrem, and have High blood pressure.

The phase IV clinical study analyzes which people have Urticaria when taking Neupro. It is created by eHealthMe based on reports of 11,313 people who have side effects when taking Neupro from the FDA, and is updated regularly.

What is Neupro?

Neupro has active ingredients of rotigotine. It is often used in parkinson's disease. eHealthMe is studying from 11,393 Neupro users. Check the latest studies of Neupro.

What is Urticaria?

Urticaria (rash of round, red welts on the skin that itch intensely) is found to be associated with 2,613 drugs and 2,954 conditions by eHealthMe. Check the latest studies of Urticaria.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

11,313 people reported to have side effects when taking Neupro.
Among them, 56 people (0.5%) have Urticaria.

Could Neupro cause Urticaria?

Among these 56 people:

How long have people been on Neupro when they have Urticaria? *

  • < 1 month: 27.27 %
  • 1 - 6 months: 72.73 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Urticaria when taking Neupro? *

  • female: 73.47 %
  • male: 26.53 %

What is the age of people who have Urticaria when taking Neupro? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.23 %
  • 40-49: 6.45 %
  • 50-59: 12.9 %
  • 60+: 77.42 %

What are other drugs people take besides Neupro? *

  1. Crestor: 6 people, 10.71%
  2. Xyrem: 6 people, 10.71%
  3. Dexilant: 5 people, 8.93%
  4. Ventolin Hfa: 5 people, 8.93%
  5. Nasonex: 5 people, 8.93%
  6. Bepreve: 5 people, 8.93%
  7. Singulair: 5 people, 8.93%
  8. Buspirone Hcl: 5 people, 8.93%
  9. Celebrex: 5 people, 8.93%
  10. Horizant: 5 people, 8.93%

What are other side effects people have besides Urticaria? *

  1. Rashes (redness): 15 people, 26.79%
  2. Itching: 13 people, 23.21%
  3. Dyspnea (difficult or laboured breathing): 5 people, 8.93%
  4. Skin Irritation: 5 people, 8.93%
  5. Nausea (feeling of having an urge to vomit): 5 people, 8.93%
  6. Application Site Pustules (small bumps on the skin that fill with fluid or pus at application site): 4 people, 7.14%
  7. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 4 people, 7.14%
  8. Constipation: 4 people, 7.14%
  9. Gamma-Glutamyltransferase Increased: 4 people, 7.14%
  10. Hair Loss: 4 people, 7.14%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 12.50%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 12.50%
  3. High Blood Pressure: 7 people, 12.50%
  4. Urination - Excessive Volume: 4 people, 7.14%
  5. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 7.14%
  6. Gastric Ulcer Perforation (stomach hole due to ulcer): 4 people, 7.14%
  7. Depression: 3 people, 5.36%
  8. On And Off Phenomenon: 3 people, 5.36%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 5.36%
  10. Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 2 people, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Neupro and have Urticaria?

- Check whether Urticaria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neupro:

Urticaria treatments and more:

How severe was Urticaria and when was it recovered:

Expand to all the drugs that have ingredients of rotigotine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Neupro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urticaria:

Browse all the conditions that are associated with Urticaria:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on rotigotine (the active ingredients of Neupro) and Neupro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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