Nevanac and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Nevanac (nepafenac), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Vasculitis.

The phase IV clinical study analyzes which people have Headache when taking Nevanac. It is created by eHealthMe based on reports of 1,729 people who have side effects when taking Nevanac from the FDA, and is updated regularly.

What is Nevanac?

Nevanac has active ingredients of nepafenac. It is often used in cataract removal. eHealthMe is studying from 1,755 Nevanac users. Check the latest studies of Nevanac.

What is Headache?

Headache (pain in head) is found to be associated with 3,751 drugs and 5,772 conditions by eHealthMe. Check the latest studies of Headache.



On Jul, 11, 2026

1,729 people reported to have side effects when taking Nevanac.
Among them, 67 people (3.88%) have Headache.

Could Nevanac cause Headache?

Among these 67 people:

How long have people been on Nevanac when they have Headache? *

  • < 1 month: 58.82 %
  • 1 - 6 months: 41.18 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Headache when taking Nevanac? *

  • female: 78.46 %
  • male: 21.54 %

What is the age of people who have Headache when taking Nevanac? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 32.2 %
  • 40-49: 3.39 %
  • 50-59: 3.39 %
  • 60+: 61.02 %

What are other drugs people take besides Nevanac? *

  1. Prednisone: 17 people, 25.37%
  2. Folic Acid: 16 people, 23.88%
  3. Prednisolone: 16 people, 23.88%
  4. Calcium: 15 people, 22.39%
  5. Methotrexate: 15 people, 22.39%
  6. Brimonidine: 14 people, 20.90%
  7. Dexamethasone: 14 people, 20.90%
  8. Mycophenolate Mofetil: 14 people, 20.90%
  9. Humira: 14 people, 20.90%
  10. Vigamox: 12 people, 17.91%

What are other side effects people have besides Headache? *

  1. Fatigue (feeling of tiredness): 26 people, 38.81%
  2. Vasculitis (inflammation of a blood vessel or blood vessels): 21 people, 31.34%
  3. Eye Pain: 21 people, 31.34%
  4. Dizziness: 19 people, 28.36%
  5. Vision Blurred: 19 people, 28.36%
  6. Visual Impairment: 18 people, 26.87%
  7. High Blood Pressure: 16 people, 23.88%
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 16 people, 23.88%
  9. Vitreous Floaters (spots before the eyes): 15 people, 22.39%
  10. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 15 people, 22.39%

What are the existing conditions these people have? *

  1. Vasculitis (inflammation of a blood vessel or blood vessels): 8 people, 11.94%
  2. Temporal Arteritis (inflammation and damage to blood vessels that supply the head area): 6 people, 8.96%
  3. High Blood Pressure: 4 people, 5.97%
  4. Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 4.48%
  5. Pain: 3 people, 4.48%
  6. Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 2.99%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 2.99%
  8. Infection: 2 people, 2.99%
  9. Neuralgia (pain in one or more nerves): 2 people, 2.99%
  10. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 2.99%

* Approximation only. Some reports may have incomplete information.

Do you take Nevanac and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nevanac:

Headache treatments and more:

How severe was Headache and when was it recovered:

Expand to all the drugs that have ingredients of nepafenac:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nevanac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Browse all the conditions that are associated with Headache:


How the study uses the data?

The study uses data from the FDA. It is based on nepafenac (the active ingredients of Nevanac) and Nevanac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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