Nevanac and Migraine aggravated - a phase IV clinical study of FDA data

Summary:

Migraine aggravated is reported as a side effect among people who take Nevanac (nepafenac), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Exelon, and have Dementia alzheimer's type.

The phase IV clinical study analyzes which people have Migraine aggravated when taking Nevanac. It is created by eHealthMe based on reports of 1,729 people who have side effects when taking Nevanac from the FDA, and is updated regularly.

What is Nevanac?

Nevanac has active ingredients of nepafenac. It is often used in cataract removal. eHealthMe is studying from 1,755 Nevanac users. Check the latest studies of Nevanac.

What is Migraine aggravated?

Migraine aggravated (headache) is found to be associated with 1,630 drugs and 482 conditions by eHealthMe. Check the latest studies of Migraine aggravated.



On Jul, 26, 2026

1,729 people reported to have side effects when taking Nevanac.
Among them, 15 people (0.87%) have Migraine aggravated.

Could Nevanac cause Migraine aggravated?

Among these 15 people:

How long have people been on Nevanac when they have Migraine aggravated? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Migraine aggravated when taking Nevanac? *

  • female: 92.86 %
  • male: 7.14 %

What is the age of people who have Migraine aggravated when taking Nevanac? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Nevanac? *

  1. Escitalopram: 12 people, 80.00%
  2. Exelon: 12 people, 80.00%
  3. Magnesium: 11 people, 73.33%
  4. Zolpidem Tartrate: 1 person, 6.67%
  5. Humira: 1 person, 6.67%
  6. Astepro: 1 person, 6.67%
  7. Atacand: 1 person, 6.67%
  8. Bystolic: 1 person, 6.67%
  9. Crestor: 1 person, 6.67%
  10. Decadron: 1 person, 6.67%

What are other side effects people have besides Migraine aggravated? *

  1. Osteopenia (a condition where bone mineral density is lower than normal): 13 people, 86.67%
  2. Nausea (feeling of having an urge to vomit): 13 people, 86.67%
  3. Weakness: 12 people, 80.00%
  4. Memory Loss: 12 people, 80.00%
  5. Acute Kidney Failure: 12 people, 80.00%
  6. Agitation (state of anxiety or nervous excitement): 12 people, 80.00%
  7. Cataract (clouding of the lens inside the eye): 12 people, 80.00%
  8. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 12 people, 80.00%
  9. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 12 people, 80.00%
  10. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 12 people, 80.00%

What are the existing conditions these people have? *

  1. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 12 people, 80.00%
  2. Depression: 11 people, 73.33%
  3. Collateral Circulation (circulation in an area of tissue or an organ with a number of different pathways for blood to reach it): 11 people, 73.33%
  4. Retinal Vascular Occlusion (a blockage of the small veins that carry blood away from the retina): 1 person, 6.67%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.67%
  6. Cluster Headache (one-sided head pain with tearing): 1 person, 6.67%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.67%
  8. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Nevanac and have Migraine aggravated?

- Check whether Migraine aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nevanac:

Migraine aggravated treatments and more:

How severe was Migraine aggravated and when was it recovered:

Expand to all the drugs that have ingredients of nepafenac:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nevanac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Migraine aggravated:

Browse all the conditions that are associated with Migraine aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on nepafenac (the active ingredients of Nevanac) and Nevanac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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