Nexavar and Nail disorder - a phase IV clinical study of FDA data

Summary:

Nail disorder is reported as a side effect among people who take Nexavar (sorafenib tosylate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Paracetamol, and have Hepatic neoplasm malignant.

The phase IV clinical study analyzes which people have Nail disorder when taking Nexavar. It is created by eHealthMe based on reports of 23,142 people who have side effects when taking Nexavar from the FDA, and is updated regularly.

What is Nexavar?

Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 23,250 Nexavar users. Check the latest studies of Nexavar.

What is Nail disorder?

Nail disorder (disease of nail) is found to be associated with 751 drugs and 1,089 conditions by eHealthMe. Check the latest studies of Nail disorder.

On Jul, 05, 2026

23,142 people reported to have side effects when taking Nexavar.
Among them, 11 people (0.05%) have Nail disorder.

Among these 11 people:

How long have people been on Nexavar when they have Nail disorder? *

What is the gender of people who have Nail disorder when taking Nexavar? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Nail disorder when taking Nexavar? *

What are other drugs people take besides Nexavar? *

What are other side effects people have besides Nail disorder? *

Diarrhea: 7 people, 63.64%
Pain In Extremity: 6 people, 54.55%
Gait Disturbance: 6 people, 54.55%
Fatigue (feeling of tiredness): 6 people, 54.55%
Hair Loss: 6 people, 54.55%
Rashes (redness): 5 people, 45.45%
Pain: 5 people, 45.45%
Skin Exfoliation (removal of the oldest dead skin cells): 5 people, 45.45%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 4 people, 36.36%
Dry Skin: 4 people, 36.36%

What are the existing conditions these people have? *

Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 2 people, 18.18%
Pain: 2 people, 18.18%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 18.18%
Hepatic Neoplasm Malignant (liver cancer): 2 people, 18.18%
Varices Oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach): 1 person, 9.09%
Metastases To Lung (cancer spreads to lung): 1 person, 9.09%
Follicular Thyroid Cancer (cancer of the thyroid): 1 person, 9.09%
Diabetes: 1 person, 9.09%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 9.09%
Breast Cancer: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Nexavar and have Nail disorder?

- Check whether Nail disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexavar:

Nexavar (23,250 reports)

Nail disorder treatments and more:

Nail disorder (9,795 reports)

Browse all side effects of Nexavar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nail disorder:

Nail disorder (751 drugs)

Browse all the conditions that are associated with Nail disorder:

Nail disorder (1,089 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sorafenib tosylate (the active ingredients of Nexavar) and Nexavar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.