Nexium 24hr and Nephrotic syndrome - a phase IV clinical study of FDA data

Summary:

Nephrotic syndrome is reported as a side effect among people who take Nexium 24hr (esomeprazole magnesium), especially for people who are male, 40-49 old, have been taking the drug for 2 - 5 years also take Nexium, and have Pain.

The phase IV clinical study analyzes which people have Nephrotic syndrome when taking Nexium 24hr. It is created by eHealthMe based on reports of 44,449 people who have side effects when taking Nexium 24hr from the FDA, and is updated regularly.

What is Nexium 24hr?

Nexium 24hr has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 44,614 Nexium 24hr users. Check the latest studies of Nexium 24hr.

What is Nephrotic syndrome?

Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema) is found to be associated with 626 drugs and 1,071 conditions by eHealthMe. Check the latest studies of Nephrotic syndrome.



On Jul, 25, 2026

44,449 people reported to have side effects when taking Nexium 24hr.
Among them, 80 people (0.18%) have Nephrotic syndrome.

Could Nexium 24hr cause Nephrotic syndrome?

Among these 80 people:

How long have people been on Nexium 24hr when they have Nephrotic syndrome? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 4.08 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 12.24 %
  • 2 - 5 years: 40.82 %
  • 5 - 10 years: 18.37 %
  • 10+ years: 24.49 %

What is the gender of people who have Nephrotic syndrome when taking Nexium 24hr? *

  • female: 46.27 %
  • male: 53.73 %

What is the age of people who have Nephrotic syndrome when taking Nexium 24hr? *

  • 0-1: 0.0 %
  • 2-9: 6.52 %
  • 10-19: 0.0 %
  • 20-29: 2.17 %
  • 30-39: 4.35 %
  • 40-49: 43.48 %
  • 50-59: 23.91 %
  • 60+: 19.57 %

What are other drugs people take besides Nexium 24hr? *

  1. Nexium: 71 people, 88.75%
  2. Prilosec: 67 people, 83.75%
  3. Prevacid: 54 people, 67.50%
  4. Prevacid 24 Hr: 48 people, 60.00%
  5. Protonix: 45 people, 56.25%
  6. Prilosec Otc: 43 people, 53.75%
  7. Pantoprazole: 21 people, 26.25%
  8. Amlodipine: 20 people, 25.00%
  9. Dexilant: 20 people, 25.00%
  10. Zantac: 15 people, 18.75%

What are other side effects people have besides Nephrotic syndrome? *

  1. Chronic Kidney Disease: 79 people, 98.75%
  2. Acute Kidney Failure: 63 people, 78.75%
  3. Nephropathy (damage to or disease of a kidney): 35 people, 43.75%
  4. Renal Impairment (severely reduced kidney function): 34 people, 42.50%
  5. Renal Injury (kidney injury): 30 people, 37.50%
  6. Diabetic Nephropathy (diabetic kidney disease): 27 people, 33.75%
  7. Nephrogenic Anaemia (anaemia due to kidney disease): 27 people, 33.75%
  8. High Blood Pressure: 18 people, 22.50%
  9. Interstitial Nephritis (inflammation of the kidney): 17 people, 21.25%
  10. Renal Disorder (kidney disease): 12 people, 15.00%

What are the existing conditions these people have? *

  1. Pain: 12 people, 15.00%
  2. Hypersensitivity: 11 people, 13.75%
  3. Indigestion: 9 people, 11.25%
  4. High Blood Pressure: 8 people, 10.00%
  5. Stress And Anxiety: 6 people, 7.50%
  6. Gastric Ulcer (stomach ulcer): 6 people, 7.50%
  7. Gastric Ph Decreased: 6 people, 7.50%
  8. High Blood Cholesterol: 5 people, 6.25%
  9. Joint Pain: 5 people, 6.25%
  10. Gastric Disorder (disease of stomach): 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium 24hr and have Nephrotic syndrome?

- Check whether Nephrotic syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexium 24hr:

Nephrotic syndrome treatments and more:

How severe was Nephrotic syndrome and when was it recovered:

Expand to all the drugs that have ingredients of esomeprazole magnesium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexium 24hr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nephrotic syndrome:

Browse all the conditions that are associated with Nephrotic syndrome:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium 24hr) and Nexium 24hr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: