Niaspan and Bleeding disorders - a phase IV clinical study of FDA data

Summary:

Bleeding disorders is reported as a side effect among people who take Niaspan (niacin), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Aspirin, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Bleeding disorders when taking Niaspan. It is created by eHealthMe based on reports of 44,502 people who have side effects when taking Niaspan from the FDA, and is updated regularly.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

What is Bleeding disorders?

Bleeding disorders is found to be associated with 1,188 drugs and 1,649 conditions by eHealthMe. Check the latest studies of Bleeding disorders.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

44,502 people reported to have side effects when taking Niaspan.
Among them, 55 people (0.12%) have Bleeding disorders.

Among these 55 people:

How long have people been on Niaspan when they have Bleeding disorders? *

What is the gender of people who have Bleeding disorders when taking Niaspan? *

female: 27.78 %
male: 72.22 %

What is the age of people who have Bleeding disorders when taking Niaspan? *

What are other drugs people take besides Niaspan? *

What are other side effects people have besides Bleeding disorders? *

Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 13 people, 23.64%
Dyspnea (difficult or laboured breathing): 13 people, 23.64%
Hypotension (abnormally low blood pressure): 9 people, 16.36%
Anaemia (lack of blood): 9 people, 16.36%
Thrombocytopenia (decrease of platelets in blood): 9 people, 16.36%
Acute Kidney Failure: 8 people, 14.55%
Nausea (feeling of having an urge to vomit): 7 people, 12.73%
Nausea And Vomiting: 7 people, 12.73%
Pain: 7 people, 12.73%
Sinusitis (inflammation of sinus): 6 people, 10.91%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 19 people, 34.55%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 10.91%
Pulmonary Embolism (blockage of the main artery of the lung): 6 people, 10.91%
Stress And Anxiety: 4 people, 7.27%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.45%
Pain: 3 people, 5.45%
Nausea (feeling of having an urge to vomit): 3 people, 5.45%
High Blood Pressure: 2 people, 3.64%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 3.64%
Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 3.64%

* Approximation only. Some reports may have incomplete information.

Do you take Niaspan and have Bleeding disorders?

- Check whether Bleeding disorders is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Niaspan:

Niaspan (45,453 reports)

Browse all side effects of Niaspan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bleeding disorders:

Bleeding disorders (1,188 drugs)

Browse all the conditions that are associated with Bleeding disorders:

Bleeding disorders (1,649 conditions)

Related publications that referenced our studies

Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on niacin (the active ingredients of Niaspan) and Niaspan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.