Niaspan and Ear pain - a phase IV clinical study of FDA data

Summary:

Ear pain is reported as a side effect among people who take Niaspan (niacin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lipitor, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Ear pain when taking Niaspan. It is created by eHealthMe based on reports of 44,502 people who have side effects when taking Niaspan from the FDA, and is updated regularly.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

What is Ear pain?

Ear pain is found to be associated with 1,391 drugs and 1,901 conditions by eHealthMe. Check the latest studies of Ear pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

44,502 people reported to have side effects when taking Niaspan.
Among them, 38 people (0.09%) have Ear pain.

Among these 38 people:

How long have people been on Niaspan when they have Ear pain? *

What is the gender of people who have Ear pain when taking Niaspan? *

female: 60.53 %
male: 39.47 %

What is the age of people who have Ear pain when taking Niaspan? *

What are other drugs people take besides Niaspan? *

What are other side effects people have besides Ear pain? *

Headache (pain in head): 14 people, 36.84%
Fall: 13 people, 34.21%
Joint Pain: 12 people, 31.58%
Neck Pain: 11 people, 28.95%
Swallowing Difficulty: 11 people, 28.95%
Gait Disturbance: 10 people, 26.32%
Skin Blushing/flushing (a sudden reddening of the face, neck): 10 people, 26.32%
Spinal Osteoarthritis (joint cartilage loss in spine): 10 people, 26.32%
Tardive Dyskinesia (a disorder that involves involuntary movements): 9 people, 23.68%
Nasal Discharge (discharge from nose): 9 people, 23.68%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 31.58%
High Blood Pressure: 7 people, 18.42%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 10.53%
High Density Lipoprotein Decreased: 3 people, 7.89%
Diabetes: 3 people, 7.89%
Osteoporosis (bones weak and more likely to break): 2 people, 5.26%
Hair Loss: 2 people, 5.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.26%
Insomnia (sleeplessness): 2 people, 5.26%
Heart Attack: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Niaspan and have Ear pain?

- Check whether Ear pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Niaspan:

Niaspan (45,453 reports)

Ear pain treatments and more:

Ear pain (26,025 reports)

Browse all side effects of Niaspan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ear pain:

Ear pain (1,391 drugs)

Browse all the conditions that are associated with Ear pain:

Ear pain (1,901 conditions)

Related publications that referenced our studies

Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on niacin (the active ingredients of Niaspan) and Niaspan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.