Niaspan and Hypertriglyceridaemia - a phase IV clinical study of FDA data

Summary:

Hypertriglyceridaemia is reported as a side effect among people who take Niaspan (niacin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Neurontin, and have Schizophrenia.

The phase IV clinical study analyzes which people have Hypertriglyceridaemia when taking Niaspan. It is created by eHealthMe based on reports of 44,502 people who have side effects when taking Niaspan from the FDA, and is updated regularly.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

What is Hypertriglyceridaemia?

Hypertriglyceridaemia (excess of triglycerides in the blood) is found to be associated with 751 drugs and 763 conditions by eHealthMe. Check the latest studies of Hypertriglyceridaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

44,502 people reported to have side effects when taking Niaspan.
Among them, 45 people (0.1%) have Hypertriglyceridaemia.

Could Niaspan cause Hypertriglyceridaemia?

Among these 45 people:

How long have people been on Niaspan when they have Hypertriglyceridaemia? *

What is the gender of people who have Hypertriglyceridaemia when taking Niaspan? *

female: 22.22 %
male: 77.78 %

What is the age of people who have Hypertriglyceridaemia when taking Niaspan? *

What are other drugs people take besides Niaspan? *

What are other side effects people have besides Hypertriglyceridaemia? *

Type 2 Diabetes: 15 people, 33.33%
Diabetes: 12 people, 26.67%
Liver Function Test Abnormal: 11 people, 24.44%
Chest Pain: 10 people, 22.22%
Dyslipidaemia (abnormal amount of lipids): 10 people, 22.22%
High Blood Pressure: 9 people, 20.00%
Erection Problems: 9 people, 20.00%
Haemoglobin Decreased: 8 people, 17.78%
Headache (pain in head): 8 people, 17.78%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 8 people, 17.78%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 12 people, 26.67%
Back Pain: 6 people, 13.33%
Bipolar Disorder (mood disorder): 6 people, 13.33%
Osteoporosis (bones weak and more likely to break): 5 people, 11.11%
Depression: 5 people, 11.11%
Nightmares (unpleasant dreams): 4 people, 8.89%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 4 people, 8.89%
Pain: 4 people, 8.89%
Muscle Aches (muscle pain): 3 people, 6.67%
Herpes Zoster: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Niaspan and have Hypertriglyceridaemia?

- Check whether Hypertriglyceridaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Niaspan:

Niaspan (45,453 reports)

Browse all side effects of Niaspan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertriglyceridaemia:

Hypertriglyceridaemia (751 drugs)

Browse all the conditions that are associated with Hypertriglyceridaemia:

Hypertriglyceridaemia (763 conditions)

Related publications that referenced our studies

Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on niacin (the active ingredients of Niaspan) and Niaspan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.