Nifedipine and Parkinson's disease - a phase IV clinical study of FDA data

Summary:

Parkinson's disease is reported as a side effect among people who take Nifedipine (nifedipine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Prilosec, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Parkinson's disease when taking Nifedipine. It is created by eHealthMe based on reports of 52,610 people who have side effects when taking Nifedipine from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

What is Parkinson's disease?

Parkinson's disease is found to be associated with 1,112 drugs and 1,629 conditions by eHealthMe. Check the latest studies of Parkinson's disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

52,610 people reported to have side effects when taking Nifedipine.
Among them, 85 people (0.16%) have Parkinson's disease.

Could Nifedipine cause Parkinson's disease?

Among these 85 people:

How long have people been on Nifedipine when they have Parkinson's disease? *

What is the gender of people who have Parkinson's disease when taking Nifedipine? *

female: 45.57 %
male: 54.43 %

What is the age of people who have Parkinson's disease when taking Nifedipine? *

What are other drugs people take besides Nifedipine? *

What are other side effects people have besides Parkinson's disease? *

Fall: 16 people, 18.82%
Weakness: 10 people, 11.76%
Acute Kidney Failure: 8 people, 9.41%
Concussion (short loss of normal brain function in response to a head injury): 8 people, 9.41%
Muscle Rigidity (muscle stiffness): 7 people, 8.24%
Memory Loss: 7 people, 8.24%
Gait Disturbance: 6 people, 7.06%
Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 7.06%
Swallowing Difficulty: 6 people, 7.06%
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases): 5 people, 5.88%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 11.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 8.24%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 4.71%
High Blood Cholesterol: 4 people, 4.71%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 3.53%
Delusion (a false belief or opinion): 3 people, 3.53%
Anaemia (lack of blood): 3 people, 3.53%
On And Off Phenomenon: 2 people, 2.35%
Osteoporosis (bones weak and more likely to break): 2 people, 2.35%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 2.35%

* Approximation only. Some reports may have incomplete information.

Do you take Nifedipine and have Parkinson's disease?

- Check whether Parkinson's disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nifedipine:

Nifedipine (53,459 reports)

Browse all side effects of Nifedipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Parkinson's disease:

Parkinson's disease (1,112 drugs)

Browse all the conditions that are associated with Parkinson's disease:

Parkinson's disease (1,629 conditions)

Related publications that referenced our studies

Woulfe JM, Gray MT, Gray DA, Munoz DG, Middeldorp JM, "Hypothesis: a role for EBV-induced molecular mimicry in Parkinson's disease", Parkinsonism & related disorders, 2014 Jul .
Woulfe JM, Gray MT, Gray DA, Munoz DG, Middeldorp JM, "Hypothesis: a role for EBV-induced molecular mimicry in Parkinson's disease", Parkinsonism & related disorders, 2014 Jul .

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine (the active ingredients of Nifedipine) and Nifedipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.