Nifedipine and Sudden death unexplained - a phase IV clinical study of FDA data

Summary:

Sudden death unexplained is reported as a side effect among people who take Nifedipine (nifedipine), especially for people who are male, 60+ old, also take Actos,.

The study is created by eHealthMe based on reports of 52,610 people who have side effects when taking Nifedipine from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

52,610 people reported to have side effects when taking Nifedipine.
Among them, 24 people (0.05%) died.

Could Nifedipine cause Sudden death unexplained?

Among these 24 people:

What is the gender of people who died when taking Nifedipine? *

female: 47.83 %
male: 52.17 %

What is the age of people who died when taking Nifedipine? *

What are other drugs people take besides Nifedipine? *

Actos: 6 people, 25.00%
Zyban: 4 people, 16.67%
Allopurinol: 4 people, 16.67%
Dipyridamole: 4 people, 16.67%
Glynase: 4 people, 16.67%
Ticlopidine Hydrochloride: 3 people, 12.50%
Minocycline Hydrochloride: 2 people, 8.33%
Dopamine Hydrochloride: 2 people, 8.33%
Enbrel: 2 people, 8.33%
Flolan: 2 people, 8.33%

What are other side effects people have before they died? *

Alanine Aminotransferase Increased: 4 people, 16.67%
Gamma-Glutamyltransferase Increased: 4 people, 16.67%
Respiratory Failure (Excl Neonatal) (inadequate gas exchange by the respiratory system(excluding neonatal)): 4 people, 16.67%
Aspartate Aminotransferase Increased: 4 people, 16.67%
Chronic Obstructive Airways Disease: 4 people, 16.67%
Diabetes Mellitus Aggravated (serious diabetes): 3 people, 12.50%
Heart Attack: 3 people, 12.50%
Stable Angina (a constant chest pain): 2 people, 8.33%
Ascites (accumulation of fluid in the abdominal cavity): 2 people, 8.33%
Liver Function Tests Nos Abnormal: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nifedipine:

Nifedipine (53,459 reports)

Expand to all the drugs that have ingredients of nifedipine:

Sudden death unexplained and drugs with ingredients of nifedipine (52 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nifedipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sudden death unexplained:

Sudden death unexplained (181 drugs)

Browse all the conditions that are associated with Sudden death unexplained:

Sudden death unexplained (24 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine (the active ingredients of Nifedipine) and Nifedipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.