Nifedipine and Ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Ventricular dysfunction is reported as a side effect among people who take Nifedipine (nifedipine), especially for people who are male, 60+ old, also take Deflazacort, and have Ill-defined disorder.

The phase IV clinical study analyzes which people have Ventricular dysfunction when taking Nifedipine. It is created by eHealthMe based on reports of 52,610 people who have side effects when taking Nifedipine from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

What is Ventricular dysfunction?

Ventricular dysfunction (heart dysfunction) is found to be associated with 449 drugs and 551 conditions by eHealthMe. Check the latest studies of Ventricular dysfunction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 03, 2026

52,610 people reported to have side effects when taking Nifedipine.
Among them, 27 people (0.05%) have Ventricular dysfunction.

Could Nifedipine cause Ventricular dysfunction?

Among these 27 people:

What is the gender of people who have Ventricular dysfunction when taking Nifedipine? *

female: 17.39 %
male: 82.61 %

What is the age of people who have Ventricular dysfunction when taking Nifedipine? *

What are other drugs people take besides Nifedipine? *

Deflazacort: 9 people, 33.33%
Hydroxychloroquine Sulfate: 2 people, 7.41%
Penicillamine: 2 people, 7.41%
Adalat: 2 people, 7.41%
Albuterol: 2 people, 7.41%
Aspirin: 2 people, 7.41%
Cardizem: 2 people, 7.41%
Diovan: 2 people, 7.41%
Enbrel: 2 people, 7.41%
Furosemide: 2 people, 7.41%

What are other side effects people have besides Ventricular dysfunction? *

Dyspnea (difficult or laboured breathing): 13 people, 48.15%
Drug Resistance (reduction in effectiveness of a drug): 13 people, 48.15%
Brain Natriuretic Peptide Increased: 12 people, 44.44%
Acute Pulmonary Oedema (sudden deposit of fluid in the lung)): 12 people, 44.44%
Tricuspid Valve Incompetence (inefficient heart valve): 12 people, 44.44%
Atrioventricular Block Complete (heart block complete): 11 people, 40.74%
Crepitations (noises are produced by the rubbing of parts one against the other): 11 people, 40.74%
Orthopnea (shortness of breath (dyspnea) when lying down): 11 people, 40.74%
Oedema (fluid collection in tissue): 11 people, 40.74%
Myocardial Fibrosis (a condition in which the heart's muscle cells are impaired): 11 people, 40.74%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.41%
Ill-Defined Disorder: 2 people, 7.41%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 3.70%
Pulmonary Oedema (fluid accumulation in the lungs): 1 person, 3.70%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 3.70%
Premature Labor: 1 person, 3.70%
Polyhydramnios (excess of amniotic fluid in the amniotic sac): 1 person, 3.70%
Labor Induction: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Nifedipine and have Ventricular dysfunction?

- Check whether Ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nifedipine:

Nifedipine (53,459 reports)

Browse all side effects of Nifedipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular dysfunction:

Ventricular dysfunction (449 drugs)

Browse all the conditions that are associated with Ventricular dysfunction:

Ventricular dysfunction (551 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine (the active ingredients of Nifedipine) and Nifedipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.