Nitisinone and Alpha 1 foetoprotein increased - a phase IV clinical study of FDA data

Summary:

Alpha 1 foetoprotein increased is reported as a side effect among people who take Nitisinone (nitisinone), especially for people who are male, 0-1 old, and have Tyrosinaemia.

The phase IV clinical study analyzes which people have Alpha 1 foetoprotein increased when taking Nitisinone. It is created by eHealthMe based on reports of 149 people who have side effects when taking Nitisinone from the FDA, and is updated regularly.

What is Nitisinone?

Nitisinone has active ingredients of nitisinone. eHealthMe is studying from 149 Nitisinone users. Check the latest studies of Nitisinone.

What is Alpha 1 foetoprotein increased?

Alpha 1 foetoprotein increased is found to be associated with 117 drugs and 205 conditions by eHealthMe. Check the latest studies of Alpha 1 foetoprotein increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

149 people reported to have side effects when taking Nitisinone.
Among them, 12 people (8.05%) have Alpha 1 foetoprotein increased.

Could Nitisinone cause Alpha 1 foetoprotein increased?

Among these 12 people:

What is the gender of people who have Alpha 1 foetoprotein increased when taking Nitisinone? *

female: 25 %
male: 75 %

What is the age of people who have Alpha 1 foetoprotein increased when taking Nitisinone? *

What are other side effects people have besides Alpha 1 foetoprotein increased? *

Hepatocellular Carcinoma (liver cancer): 7 people, 58.33%
Hepatic Failure (liver failure): 4 people, 33.33%
Pulmonary Haemorrhage (acute bleeding from the lung): 1 person, 8.33%
Hepatic Mass: 1 person, 8.33%
Dysplasia (enlargement of an organ or tissue): 1 person, 8.33%
Drug Ineffective: 1 person, 8.33%

What are the existing conditions these people have? *

Tyrosinaemia (tyrosine metabolism resulting in liver and kidney disturbances and mental retardation): 11 people, 91.67%
Renal Tubular Acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Nitisinone and have Alpha 1 foetoprotein increased?

- Check whether Alpha 1 foetoprotein increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nitisinone:

Nitisinone (149 reports)

Browse all side effects of Nitisinone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Alpha 1 foetoprotein increased:

Alpha 1 foetoprotein increased (117 drugs)

Browse all the conditions that are associated with Alpha 1 foetoprotein increased:

Alpha 1 foetoprotein increased (205 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitisinone (the active ingredients of Nitisinone) and Nitisinone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.