Nitrofurantoin and Heart rate increased - a phase IV clinical study of FDA data

Summary:

Heart rate increased is reported as a side effect among people who take Nitrofurantoin (nitrofurantoin, macrocrystalline), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Diazepam, and have Osteoporosis.

The phase IV clinical study analyzes which people have Heart rate increased when taking Nitrofurantoin. It is created by eHealthMe based on reports of 4,140 people who have side effects when taking Nitrofurantoin from the FDA, and is updated regularly.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

What is Heart rate increased?

Heart rate increased is found to be associated with 2,385 drugs and 3,212 conditions by eHealthMe. Check the latest studies of Heart rate increased.

On Jul, 12, 2026

4,140 people reported to have side effects when taking Nitrofurantoin.
Among them, 57 people (1.38%) have Heart rate increased.

Could Nitrofurantoin cause Heart rate increased?

Among these 57 people:

How long have people been on Nitrofurantoin when they have Heart rate increased? *

What is the gender of people who have Heart rate increased when taking Nitrofurantoin? *

female: 98.25 %
male: 1.75 %

What is the age of people who have Heart rate increased when taking Nitrofurantoin? *

What are other drugs people take besides Nitrofurantoin? *

What are other side effects people have besides Heart rate increased? *

Dyspnea (difficult or laboured breathing): 35 people, 61.40%
High Blood Pressure: 32 people, 56.14%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 30 people, 52.63%
Diarrhea: 30 people, 52.63%
Pain: 28 people, 49.12%
Stress And Anxiety: 28 people, 49.12%
Malaise (a feeling of general discomfort or uneasiness): 27 people, 47.37%
Cough: 26 people, 45.61%
Speech Disorder: 26 people, 45.61%
Muscle Aches (muscle pain): 26 people, 45.61%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 25 people, 43.86%
Nausea And Vomiting: 3 people, 5.26%
Drowsiness: 2 people, 3.51%
Nausea (feeling of having an urge to vomit): 2 people, 3.51%
High Blood Pressure: 2 people, 3.51%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 1 person, 1.75%
Diarrhea: 1 person, 1.75%
Dermatitis Allergic (inflammation of the skin due allergic reaction): 1 person, 1.75%
Constipation: 1 person, 1.75%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 1.75%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrofurantoin and have Heart rate increased?

- Check whether Heart rate increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nitrofurantoin:

Nitrofurantoin (4,837 reports)

Heart rate increased treatments and more:

Heart rate increased (126,750 reports)

How severe was Heart rate increased and when was it recovered:

Heart rate increased in Nitrofurantoin

Expand to all the drugs that have ingredients of nitrofurantoin, macrocrystalline:

Heart rate increased and drugs with ingredients of nitrofurantoin, macrocrystalline (84 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrofurantoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart rate increased:

Heart rate increased (2,385 drugs)

Browse all the conditions that are associated with Heart rate increased:

Heart rate increased (3,212 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin, macrocrystalline (the active ingredients of Nitrofurantoin) and Nitrofurantoin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.