Nitrofurantoin and Pneumonia aspiration - a phase IV clinical study of FDA data

Summary:

Pneumonia aspiration is reported as a side effect among people who take Nitrofurantoin (nitrofurantoin, macrocrystalline), especially for people who are female, 60+ old, also take Digoxin, and have Heart rate irregular.

The phase IV clinical study analyzes which people have Pneumonia aspiration when taking Nitrofurantoin. It is created by eHealthMe based on reports of 4,140 people who have side effects when taking Nitrofurantoin from the FDA, and is updated regularly.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,840 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

What is Pneumonia aspiration?

Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree) is found to be associated with 1,395 drugs and 1,617 conditions by eHealthMe. Check the latest studies of Pneumonia aspiration.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

4,140 people reported to have side effects when taking Nitrofurantoin.
Among them, 26 people (0.63%) have Pneumonia aspiration.

Could Nitrofurantoin cause Pneumonia aspiration?

Among these 26 people:

What is the gender of people who have Pneumonia aspiration when taking Nitrofurantoin? *

female: 72 %
male: 28 %

What is the age of people who have Pneumonia aspiration when taking Nitrofurantoin? *

What are other drugs people take besides Nitrofurantoin? *

Digoxin: 12 people, 46.15%
Lasix: 11 people, 42.31%
Aspirin: 10 people, 38.46%
Lisinopril: 9 people, 34.62%
Azithromycin: 8 people, 30.77%
Naproxen: 8 people, 30.77%
Ibuprofen: 8 people, 30.77%
Fluticasone Propionate: 8 people, 30.77%
Flexeril: 6 people, 23.08%
Topamax: 6 people, 23.08%

What are other side effects people have besides Pneumonia aspiration? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 50.00%
Glaucoma (increased fluid pressure in the eye with vision loss): 12 people, 46.15%
Cardiac Failure Congestive: 11 people, 42.31%
Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth): 9 people, 34.62%
Pain: 9 people, 34.62%
Developmental Delay: 8 people, 30.77%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 30.77%
Bronchial Hyperreactivity: 8 people, 30.77%
Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 7 people, 26.92%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 7 people, 26.92%

What are the existing conditions these people have? *

Sciatic Nerve Injury: 5 people, 19.23%
Heart Rate Irregular: 5 people, 19.23%
Migraine (headache): 4 people, 15.38%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 3 people, 11.54%
Sleep Disorder: 2 people, 7.69%
Dementia (madness): 2 people, 7.69%
Stress And Anxiety: 1 person, 3.85%
High Blood Pressure: 1 person, 3.85%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 3.85%
Erythema Nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrofurantoin and have Pneumonia aspiration?

- Check whether Pneumonia aspiration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nitrofurantoin:

Nitrofurantoin (4,840 reports)

Pneumonia aspiration treatments and more:

Pneumonia aspiration (30,715 reports)

How severe was Pneumonia aspiration and when was it recovered:

Pneumonia aspiration in Nitrofurantoin

Expand to all the drugs that have ingredients of nitrofurantoin, macrocrystalline:

Pneumonia aspiration and drugs with ingredients of nitrofurantoin, macrocrystalline (35 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrofurantoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pneumonia aspiration:

Pneumonia aspiration (1,395 drugs)

Browse all the conditions that are associated with Pneumonia aspiration:

Pneumonia aspiration (1,617 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin, macrocrystalline (the active ingredients of Nitrofurantoin) and Nitrofurantoin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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