Nitrostat and Adrenal insufficiency - a phase IV clinical study of FDA data

Summary:

Adrenal insufficiency is reported as a side effect among people who take Nitrostat (nitroglycerin), especially for people who are female, 60+ old, also take Synthroid, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Adrenal insufficiency when taking Nitrostat. It is created by eHealthMe based on reports of 14,000 people who have side effects when taking Nitrostat from the FDA, and is updated regularly.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

What is Adrenal insufficiency?

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids) is found to be associated with 968 drugs and 1,092 conditions by eHealthMe. Check the latest studies of Adrenal insufficiency.

On Jul, 06, 2026

14,000 people reported to have side effects when taking Nitrostat.
Among them, 14 people (0.1%) have Adrenal insufficiency.

Could Nitrostat cause Adrenal insufficiency?

Among these 14 people:

What is the gender of people who have Adrenal insufficiency when taking Nitrostat? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Adrenal insufficiency when taking Nitrostat? *

What are other drugs people take besides Nitrostat? *

What are other side effects people have besides Adrenal insufficiency? *

Head Injury: 11 people, 78.57%
Dizziness: 10 people, 71.43%
Dyspnea (difficult or laboured breathing): 9 people, 64.29%
Abdominal Pain: 9 people, 64.29%
Gastritis (inflammation of stomach): 8 people, 57.14%
Diarrhea: 7 people, 50.00%
Depression: 7 people, 50.00%
Septic Shock (shock due to blood infection): 7 people, 50.00%
Transaminases Increased: 7 people, 50.00%
Nausea (feeling of having an urge to vomit): 7 people, 50.00%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 35.71%
Cardiac Disorder: 4 people, 28.57%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 28.57%
Diabetes: 4 people, 28.57%
Thyroid Diseases: 2 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 14.29%
Depression: 2 people, 14.29%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 14.29%
High Blood Pressure: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrostat and have Adrenal insufficiency?

- Check whether Adrenal insufficiency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nitrostat:

Nitrostat (14,082 reports)

Browse all side effects of Nitrostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adrenal insufficiency:

Adrenal insufficiency (968 drugs)

Browse all the conditions that are associated with Adrenal insufficiency:

Adrenal insufficiency (1,092 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin (the active ingredients of Nitrostat) and Nitrostat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.