Norco and Erythema multiforme - a phase IV clinical study of FDA data

Summary:

Erythema multiforme is reported as a side effect among people who take Norco (acetaminophen; hydrocodone bitartrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Erythema multiforme when taking Norco. It is created by eHealthMe based on reports of 71,619 people who have side effects when taking Norco from the FDA, and is updated regularly.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.

What is Erythema multiforme?

Erythema multiforme (a type of hypersensitivity reaction) is found to be associated with 1,693 drugs and 2,922 conditions by eHealthMe. Check the latest studies of Erythema multiforme.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 16, 2026

71,619 people reported to have side effects when taking Norco.
Among them, 53 people (0.07%) have Erythema multiforme.

Among these 53 people:

How long have people been on Norco when they have Erythema multiforme? *

What is the gender of people who have Erythema multiforme when taking Norco? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Erythema multiforme when taking Norco? *

What are other drugs people take besides Norco? *

What are other side effects people have besides Erythema multiforme? *

Fatigue (feeling of tiredness): 9 people, 16.98%
Fever: 8 people, 15.09%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 7 people, 13.21%
Rashes (redness): 7 people, 13.21%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 13.21%
Sinusitis (inflammation of sinus): 6 people, 11.32%
High Blood Pressure: 6 people, 11.32%
Peripheral Swelling: 5 people, 9.43%
Neuralgia (pain in one or more nerves): 5 people, 9.43%
Pain In Extremity: 5 people, 9.43%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 13.21%
Sleep Disorder: 6 people, 11.32%
Cough: 5 people, 9.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.43%
Nausea (feeling of having an urge to vomit): 5 people, 9.43%
Osteoporosis (bones weak and more likely to break): 4 people, 7.55%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 7.55%
High Blood Pressure: 4 people, 7.55%
Stress And Anxiety: 4 people, 7.55%
High Blood Cholesterol: 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Norco and have Erythema multiforme?

- Check whether Erythema multiforme is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norco:

Norco (74,063 reports)

Erythema multiforme treatments and more:

Erythema multiforme (56,072 reports)

How severe was Erythema multiforme and when was it recovered:

Erythema multiforme in Norco

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Erythema multiforme and drugs with ingredients of acetaminophen; hydrocodone bitartrate (293 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norco:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Norco) and Norco (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.