Norethindrone acetate and Vaginal bleeding between periods - a phase IV clinical study of FDA data

Summary:

Vaginal bleeding between periods is reported as a side effect among people who take Norethindrone acetate (norethindrone acetate), especially for people who are 30-39 old, have been taking the drug for 1 - 6 months also take Lupron Depot, and have Pain.

The phase IV clinical study analyzes which people have Vaginal bleeding between periods when taking Norethindrone acetate. It is created by eHealthMe based on reports of 677 people who have side effects when taking Norethindrone acetate from the FDA, and is updated regularly.

What is Norethindrone acetate?

Norethindrone acetate has active ingredients of norethindrone acetate. It is often used in bleeding. eHealthMe is studying from 738 Norethindrone acetate users. Check the latest studies of Norethindrone acetate.

What is Vaginal bleeding between periods?

Vaginal bleeding between periods is found to be associated with 574 drugs and 1,469 conditions by eHealthMe. Check the latest studies of Vaginal bleeding between periods.



On Aug, 04, 2026

677 people reported to have side effects when taking Norethindrone acetate.
Among them, 25 people (3.69%) have Vaginal bleeding between periods.

Could Norethindrone acetate cause Vaginal bleeding between periods?

Among these 25 people:

How long have people been on Norethindrone acetate when they have Vaginal bleeding between periods? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Vaginal bleeding between periods when taking Norethindrone acetate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 15.79 %
  • 20-29: 21.05 %
  • 30-39: 57.89 %
  • 40-49: 5.26 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Norethindrone acetate? *

  1. Lupron Depot: 18 people, 72.00%
  2. Calcium: 4 people, 16.00%
  3. Potassium: 3 people, 12.00%
  4. Ibuprofen: 3 people, 12.00%
  5. Multivitamin: 3 people, 12.00%
  6. Magnesium: 2 people, 8.00%
  7. Metformin: 2 people, 8.00%
  8. Lexapro: 2 people, 8.00%
  9. Vitamin D: 2 people, 8.00%
  10. Cephalexin: 1 person, 4.00%

What are other side effects people have besides Vaginal bleeding between periods? *

  1. Heavy Or Prolong Menstrual Bleeding: 5 people, 20.00%
  2. Vaginal Bleeding: 5 people, 20.00%
  3. Hot Flush (sudden feelings of heat): 5 people, 20.00%
  4. Muscle Spasms (muscle contraction): 4 people, 16.00%
  5. Abdominal Pain: 4 people, 16.00%
  6. Drug Ineffective: 4 people, 16.00%
  7. Mood Swings (an extreme or rapid change in mood): 4 people, 16.00%
  8. Migraine (headache): 4 people, 16.00%
  9. Nausea (feeling of having an urge to vomit): 4 people, 16.00%
  10. Pelvic Pain: 4 people, 16.00%

What are the existing conditions these people have? *

  1. Pain: 4 people, 16.00%
  2. Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 2 people, 8.00%
  3. Stress And Anxiety: 2 people, 8.00%
  4. Nausea And Vomiting: 2 people, 8.00%
  5. Nausea (feeling of having an urge to vomit): 2 people, 8.00%
  6. Depression: 2 people, 8.00%
  7. Muscle Spasms (muscle contraction): 1 person, 4.00%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 4.00%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.00%
  10. Diarrhea: 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Norethindrone acetate and have Vaginal bleeding between periods?

- Check whether Vaginal bleeding between periods is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norethindrone acetate:

Vaginal bleeding between periods treatments and more:

How severe was Vaginal bleeding between periods and when was it recovered:

Expand to all the drugs that have ingredients of norethindrone acetate:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norethindrone acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vaginal bleeding between periods:

Browse all the conditions that are associated with Vaginal bleeding between periods:


How the study uses the data?

The study uses data from the FDA. It is based on norethindrone acetate (the active ingredients of Norethindrone acetate) and Norethindrone acetate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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