Norfloxacin and Tendon rupture - a phase IV clinical study of FDA data
Summary:
Tendon rupture is reported as a side effect among people who take Norfloxacin (norfloxacin), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Flagyl, and have Otitis externa.
The phase IV clinical study analyzes which people have Tendon rupture when taking Norfloxacin. It is created by eHealthMe based on reports of 2,513 people who have side effects when taking Norfloxacin from the FDA, and is updated regularly.
What is Norfloxacin?
Norfloxacin has active ingredients of norfloxacin. It is often used in urinary tract infection. eHealthMe is studying from 2,567 Norfloxacin users. Check the latest studies of Norfloxacin.
What is Tendon rupture?
Tendon rupture (tear of tendon) is found to be associated with 804 drugs and 1,060 conditions by eHealthMe. Check the latest studies of Tendon rupture.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
2,513 people reported to have side effects when taking Norfloxacin.
Among them, 22 people (0.88%) have Tendon rupture.

Among these 22 people:
How long have people been on Norfloxacin when they have Tendon rupture? *
- < 1 month: 30 %
- 1 - 6 months: 70 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Tendon rupture when taking Norfloxacin? *
- female: 23.81 %
- male: 76.19 %
What is the age of people who have Tendon rupture when taking Norfloxacin? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 7.69 %
- 50-59: 30.77 %
- 60+: 61.54 %
What are other drugs people take besides Norfloxacin? *
- Metformin: 4 people, 18.18%
- Augmentin: 4 people, 18.18%
- Bactrim: 4 people, 18.18%
- Flagyl: 4 people, 18.18%
- Ketoprofen: 3 people, 13.64%
- Aldactone: 3 people, 13.64%
- Trandolapril: 3 people, 13.64%
- Losartan: 3 people, 13.64%
- Acetaminophen: 3 people, 13.64%
- Ofloxacin: 3 people, 13.64%
What are other side effects people have besides Tendon rupture? *
- Tendonitis (a condition that causes pain and swelling of tendons): 20 people, 90.91%
- Joint Pain: 19 people, 86.36%
- Neuropathy Peripheral (surface nerve damage): 17 people, 77.27%
- Muscle Aches (muscle pain): 17 people, 77.27%
- Joint Swelling: 12 people, 54.55%
- Electrocardiogram Qt Prolonged: 10 people, 45.45%
- Fatigue (feeling of tiredness): 9 people, 40.91%
- High Blood Pressure: 9 people, 40.91%
- Headache (pain in head): 9 people, 40.91%
- Pain In Extremity: 7 people, 31.82%
What are the existing conditions these people have? *
- Prostatitis (inflammation of the prostate gland): 7 people, 31.82%
- Otitis Externa (external ear infection): 7 people, 31.82%
- High Blood Pressure: 4 people, 18.18%
- Diabetes: 4 people, 18.18%
- Escherichia Urinary Tract Infection (urinary tract infection by escherichia coli): 3 people, 13.64%
- Pain: 2 people, 9.09%
- Insomnia (sleeplessness): 2 people, 9.09%
- Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 9.09%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.09%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Norfloxacin and have Tendon rupture?
- Check whether Tendon rupture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Norfloxacin:
- Norfloxacin (2,567 reports)
Tendon rupture treatments and more:
- Tendon rupture (15,907 reports)
How severe was Tendon rupture and when was it recovered:
Expand to all the drugs that have ingredients of norfloxacin:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Norfloxacin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Tendon rupture:
- Tendon rupture (804 drugs)
Browse all the conditions that are associated with Tendon rupture:
- Tendon rupture (1,060 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on norfloxacin (the active ingredients of Norfloxacin) and Norfloxacin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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