Norgesic and Depression aggravated - a phase IV clinical study of FDA data

Summary:

Depression aggravated is reported as a side effect among people who take Norgesic (aspirin; caffeine; orphenadrine citrate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Vicodin, and have Joint pain.

The phase IV clinical study analyzes which people have Depression aggravated when taking Norgesic. It is created by eHealthMe based on reports of 284 people who have side effects when taking Norgesic from the FDA, and is updated regularly.

What is Norgesic?

Norgesic has active ingredients of aspirin; caffeine; orphenadrine citrate. eHealthMe is studying from 330 Norgesic users. Check the latest studies of Norgesic.

What is Depression aggravated?

Depression aggravated is found to be associated with 2,407 drugs and 750 conditions by eHealthMe. Check the latest studies of Depression aggravated.

On Aug, 09, 2026

284 people reported to have side effects when taking Norgesic.
Among them, 13 people (4.58%) have Depression aggravated.

Could Norgesic cause Depression aggravated?

Among these 13 people:

How long have people been on Norgesic when they have Depression aggravated? *

What is the gender of people who have Depression aggravated when taking Norgesic? *

female: 69.23 %
male: 30.77 %

What is the age of people who have Depression aggravated when taking Norgesic? *

What are other drugs people take besides Norgesic? *

What are other side effects people have besides Depression aggravated? *

Weight Increased: 4 people, 30.77%
Chest Pain: 4 people, 30.77%
Fall: 4 people, 30.77%
Photophobia (extreme sensitivity to light): 4 people, 30.77%
Stress Symptoms: 4 people, 30.77%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 30.77%
Fever: 4 people, 30.77%
Herpes Zoster: 4 people, 30.77%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 30.77%
Blood In Stool: 4 people, 30.77%

What are the existing conditions these people have? *

Joint Pain: 2 people, 15.38%
Neuralgia (pain in one or more nerves): 1 person, 7.69%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
Migraine (headache): 1 person, 7.69%
Headache (pain in head): 1 person, 7.69%
Breakthrough Pain: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Norgesic and have Depression aggravated?

- Check whether Depression aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norgesic:

Norgesic (330 reports)

Depression aggravated treatments and more:

Depression aggravated (2,253 reports)

How severe was Depression aggravated and when was it recovered:

Depression aggravated in Norgesic

Expand to all the drugs that have ingredients of aspirin; caffeine; orphenadrine citrate:

Depression aggravated and drugs with ingredients of aspirin; caffeine; orphenadrine citrate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norgesic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression aggravated:

Depression aggravated (2,408 drugs)

Browse all the conditions that are associated with Depression aggravated:

Depression aggravated (750 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aspirin; caffeine; orphenadrine citrate (the active ingredients of Norgesic) and Norgesic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.