Normodyne and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Normodyne (labetalol hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lasix, and have Breast cancer.

The study is created by eHealthMe based on reports of 853 people who have side effects when taking Normodyne from the FDA, and is updated regularly.

What is Normodyne?

Normodyne has active ingredients of labetalol hydrochloride. eHealthMe is studying from 858 Normodyne users. Check the latest studies of Normodyne.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

853 people reported to have side effects when taking Normodyne.
Among them, 30 people (3.52%) died.

Among these 30 people:

How long have people been on Normodyne when they died? *

What is the gender of people who died when taking Normodyne? *

female: 66.67 %
male: 33.33 %

What is the age of people who died when taking Normodyne? *

What are other drugs people take besides Normodyne? *

What are other side effects people have before they died? *

Pain: 13 people, 43.33%
Anaemia (lack of blood): 11 people, 36.67%
High Blood Pressure: 11 people, 36.67%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 10 people, 33.33%
Chest Pain: 10 people, 33.33%
Joint Pain: 10 people, 33.33%
Insomnia (sleeplessness): 10 people, 33.33%
Indigestion: 10 people, 33.33%
Fatigue (feeling of tiredness): 10 people, 33.33%
Dyspnea (difficult or laboured breathing): 10 people, 33.33%

What are the existing conditions these people have? *

Breast Cancer: 9 people, 30.00%
Diarrhea: 4 people, 13.33%
Nausea (feeling of having an urge to vomit): 3 people, 10.00%
Pain: 3 people, 10.00%
Indigestion: 3 people, 10.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 6.67%
Blood Pressure Abnormal: 2 people, 6.67%
Constipation: 2 people, 6.67%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 6.67%
Chronic Kidney Disease: 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Normodyne:

Normodyne (858 reports)

Expand to all the drugs that have ingredients of labetalol hydrochloride:

Death and drugs with ingredients of labetalol hydrochloride (612 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Normodyne:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,106 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on labetalol hydrochloride (the active ingredients of Normodyne) and Normodyne (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.