Norpace and Hypotension - a phase IV clinical study of FDA data

Summary:

Hypotension is reported as a side effect among people who take Norpace (disopyramide phosphate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Arrhythmias.

The phase IV clinical study analyzes which people have Hypotension when taking Norpace. It is created by eHealthMe based on reports of 1,146 people who have side effects when taking Norpace from the FDA, and is updated regularly.

What is Norpace?

Norpace has active ingredients of disopyramide phosphate. eHealthMe is studying from 1,179 Norpace users. Check the latest studies of Norpace.

What is Hypotension?

Hypotension (abnormally low blood pressure) is found to be associated with 3,357 drugs and 4,756 conditions by eHealthMe. Check the latest studies of Hypotension.



On Jul, 21, 2026

1,146 people reported to have side effects when taking Norpace.
Among them, 28 people (2.44%) have Hypotension.

Could Norpace cause Hypotension?

Among these 28 people:

How long have people been on Norpace when they have Hypotension? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypotension when taking Norpace? *

  • female: 39.29 %
  • male: 60.71 %

What is the age of people who have Hypotension when taking Norpace? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 8.7 %
  • 30-39: 4.35 %
  • 40-49: 13.04 %
  • 50-59: 13.04 %
  • 60+: 60.87 %

What are other drugs people take besides Norpace? *

  1. Aspirin: 7 people, 25.00%
  2. Ranitidine Hydrochloride: 4 people, 14.29%
  3. Simvastatin: 4 people, 14.29%
  4. Singulair: 4 people, 14.29%
  5. Albuterol Sulfate: 4 people, 14.29%
  6. Allopurinol: 4 people, 14.29%
  7. Toprol-Xl: 3 people, 10.71%
  8. Diazepam: 3 people, 10.71%
  9. Benzonatate: 3 people, 10.71%
  10. Tamiflu: 3 people, 10.71%

What are other side effects people have besides Hypotension? *

  1. Dizziness: 8 people, 28.57%
  2. Muscle Aches (muscle pain): 5 people, 17.86%
  3. Heart Rate Decreased: 5 people, 17.86%
  4. Heart Attack: 5 people, 17.86%
  5. Headache (pain in head): 5 people, 17.86%
  6. Loss Of Consciousness: 5 people, 17.86%
  7. Fainting (loss of consciousness and postural tone): 5 people, 17.86%
  8. Sleep Apnea Syndrome: 4 people, 14.29%
  9. Pain In Extremity: 4 people, 14.29%
  10. High Blood Pressure: 4 people, 14.29%

What are the existing conditions these people have? *

  1. Arrhythmias (irregular heartbeat): 6 people, 21.43%
  2. Hypertrophic Cardiomyopathy (a condition in which the heart muscle becomes abnormally thick): 5 people, 17.86%
  3. Nasal Discharge (discharge from nose): 3 people, 10.71%
  4. High Blood Cholesterol: 2 people, 7.14%
  5. Subacute Endocarditis (bacterial infection that produces growths on the endocardium (the cells lining the inside of the heart)): 2 people, 7.14%
  6. Presyncope: 2 people, 7.14%
  7. Birth Control: 2 people, 7.14%
  8. Cardiac Disorder: 2 people, 7.14%
  9. Gout (uric acid crystals building up in the body): 2 people, 7.14%
  10. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Norpace and have Hypotension?

- Check whether Hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norpace:

Hypotension treatments and more:

How severe was Hypotension and when was it recovered:

Expand to all the drugs that have ingredients of disopyramide phosphate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norpace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotension:

Browse all the conditions that are associated with Hypotension:


How the study uses the data?

The study uses data from the FDA. It is based on disopyramide phosphate (the active ingredients of Norpace) and Norpace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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