Norplant and Pseudotumor cerebri - a phase IV clinical study of FDA data

Summary:

Pseudotumor cerebri is reported as a side effect among people who take Norplant (levonorgestrel), especially for people who are female, 20-29 old, have been taking the drug for 2 - 5 years also take Ibuprofen,.

The phase IV clinical study analyzes which people have Pseudotumor cerebri when taking Norplant. It is created by eHealthMe based on reports of 6,416 people who have side effects when taking Norplant from the FDA, and is updated regularly.

What is Norplant?

Norplant has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 6,430 Norplant users. Check the latest studies of Norplant.

What is Pseudotumor cerebri?

Pseudotumor cerebri (increased pressure within the brain in the absence of a tumour) is found to be associated with 293 drugs and 923 conditions by eHealthMe. Check the latest studies of Pseudotumor cerebri.

On Jul, 14, 2026

6,416 people reported to have side effects when taking Norplant.
Among them, 13 people (0.2%) have Pseudotumor cerebri.

Could Norplant cause Pseudotumor cerebri?

Among these 13 people:

How long have people been on Norplant when they have Pseudotumor cerebri? *

What is the gender of people who have Pseudotumor cerebri when taking Norplant? *

female: 100 %
male: 0.0 %

What is the age of people who have Pseudotumor cerebri when taking Norplant? *

What are other drugs people take besides Norplant? *

Ibuprofen: 2 people, 15.38%
Zocor: 1 person, 7.69%
Vitamin E: 1 person, 7.69%

What are other side effects people have besides Pseudotumor cerebri? *

Weight Increased: 6 people, 46.15%
Neck Pain: 4 people, 30.77%
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal): 3 people, 23.08%
Eye Pain: 3 people, 23.08%
Nausea (feeling of having an urge to vomit): 3 people, 23.08%
Ovarian Cysts (fluid filled sacs of the ovary): 2 people, 15.38%
Diplopia (double vision): 2 people, 15.38%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 15.38%
Fatigue (feeling of tiredness): 2 people, 15.38%
Dysmenorrhea (painful menstruation): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Norplant and have Pseudotumor cerebri?

- Check whether Pseudotumor cerebri is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norplant:

Norplant (6,430 reports)

Browse all side effects of Norplant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pseudotumor cerebri:

Pseudotumor cerebri (293 drugs)

Browse all the conditions that are associated with Pseudotumor cerebri:

Pseudotumor cerebri (923 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel (the active ingredients of Norplant) and Norplant (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.