Norpramin and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Norpramin (desipramine hydrochloride), especially for people who are female, 50-59 old, also take Fosamax, and have Osteoporosis.

The phase IV clinical study analyzes which people have Joint pain when taking Norpramin. It is created by eHealthMe based on reports of 262 people who have side effects when taking Norpramin from the FDA, and is updated regularly.

What is Norpramin?

Norpramin has active ingredients of desipramine hydrochloride. It is often used in depression. eHealthMe is studying from 272 Norpramin users. Check the latest studies of Norpramin.

What is Joint pain?

Joint pain is found to be associated with 3,327 drugs and 5,213 conditions by eHealthMe. Check the latest studies of Joint pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 27, 2026

262 people reported to have side effects when taking Norpramin.
Among them, 12 people (4.58%) have Joint pain.

Among these 12 people:

What is the gender of people who have Joint pain when taking Norpramin? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Joint pain when taking Norpramin? *

What are other drugs people take besides Norpramin? *

What are other side effects people have besides Joint pain? *

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 8 people, 66.67%
Fatigue (feeling of tiredness): 7 people, 58.33%
Back Pain: 6 people, 50.00%
Neuropathy Peripheral (surface nerve damage): 6 people, 50.00%
Joint Swelling: 5 people, 41.67%
Type 2 Diabetes: 4 people, 33.33%
Femur Fracture: 4 people, 33.33%
Weakness: 4 people, 33.33%
High Blood Pressure: 4 people, 33.33%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 25.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 33.33%
Pain In Extremity: 3 people, 25.00%
Hypophosphatasia (metabolic bone disease): 3 people, 25.00%
Back Pain: 3 people, 25.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 16.67%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 8.33%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 8.33%
Panic Disorder: 1 person, 8.33%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 8.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Norpramin and have Joint pain?

- Check whether Joint pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norpramin:

Norpramin (272 reports)

Joint pain treatments and more:

Joint pain (542,936 reports)

Browse all side effects of Norpramin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Joint pain (3,327 drugs)

Browse all the conditions that are associated with Joint pain:

Joint pain (5,213 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on desipramine hydrochloride (the active ingredients of Norpramin) and Norpramin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.