Northera and Muscle aches - a phase IV clinical study of FDA data

Summary:

Muscle aches is reported as a side effect among people who take Northera (droxidopa), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin B12, and have Orthostatic hypotension.

The phase IV clinical study analyzes which people have Muscle aches when taking Northera. It is created by eHealthMe based on reports of 22,868 people who have side effects when taking Northera from the FDA, and is updated regularly.

What is Northera?

Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.

What is Muscle aches?

Muscle aches (muscle pain) is found to be associated with 2,721 drugs and 3,741 conditions by eHealthMe. Check the latest studies of Muscle aches.

On Jul, 15, 2026

22,868 people reported to have side effects when taking Northera.
Among them, 89 people (0.39%) have Muscle aches.

Among these 89 people:

How long have people been on Northera when they have Muscle aches? *

What is the gender of people who have Muscle aches when taking Northera? *

female: 64.04 %
male: 35.96 %

What is the age of people who have Muscle aches when taking Northera? *

What are other drugs people take besides Northera? *

What are other side effects people have besides Muscle aches? *

Dizziness: 31 people, 34.83%
Fatigue (feeling of tiredness): 30 people, 33.71%
Headache (pain in head): 26 people, 29.21%
Nausea (feeling of having an urge to vomit): 18 people, 20.22%
High Blood Pressure: 16 people, 17.98%
Weakness: 14 people, 15.73%
Feeling Abnormal: 13 people, 14.61%
Muscle Spasms (muscle contraction): 12 people, 13.48%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 11 people, 12.36%
Chest Pain: 11 people, 12.36%

What are the existing conditions these people have? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 34 people, 38.20%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 11 people, 12.36%
Autonomic Failure Syndrome (a degenerative disease of the autonomic nervous system): 7 people, 7.87%
Fainting (loss of consciousness and postural tone): 5 people, 5.62%
Hypotension (abnormally low blood pressure): 4 people, 4.49%
High Blood Cholesterol: 4 people, 4.49%
Parkinson's Disease: 4 people, 4.49%
Neuropathy Peripheral (surface nerve damage): 3 people, 3.37%
Postural Orthostatic Tachycardia Syndrome (abnormal increase in heart rate on becoming upright): 3 people, 3.37%
Dizziness: 3 people, 3.37%

* Approximation only. Some reports may have incomplete information.

Do you take Northera and have Muscle aches?

- Check whether Muscle aches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Northera:

Northera (22,874 reports)

Muscle aches treatments and more:

Muscle aches (219,259 reports)

Browse all side effects of Northera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle aches:

Muscle aches (2,721 drugs)

Browse all the conditions that are associated with Muscle aches:

Muscle aches (3,741 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on droxidopa (the active ingredients of Northera) and Northera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.