Nortriptyline hydrochloride and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Nortriptyline hydrochloride (nortriptyline hydrochloride), especially for people who are 60+ old, have been taking the drug for 10+ years also take Fish Oil, and have Fibromyalgia.

The phase IV clinical study analyzes which people have Hot flush when taking Nortriptyline hydrochloride. It is created by eHealthMe based on reports of 3,475 people who have side effects when taking Nortriptyline hydrochloride from the FDA, and is updated regularly.

What is Nortriptyline hydrochloride?

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,817 Nortriptyline hydrochloride users. Check the latest studies of Nortriptyline hydrochloride.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,771 drugs and 2,347 conditions by eHealthMe. Check the latest studies of Hot flush.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

3,475 people reported to have side effects when taking Nortriptyline hydrochloride.
Among them, 17 people (0.49%) have Hot flush.

Could Nortriptyline hydrochloride cause Hot flush?

Among these 17 people:

How long have people been on Nortriptyline hydrochloride when they have Hot flush? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

What is the age of people who have Hot flush when taking Nortriptyline hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.14 %
  • 50-59: 7.14 %
  • 60+: 85.71 %

What are other drugs people take besides Nortriptyline hydrochloride? *

  1. Fish Oil: 11 people, 64.71%
  2. Fluconazole: 10 people, 58.82%
  3. Zometa: 9 people, 52.94%
  4. Thalomid: 9 people, 52.94%
  5. Nystatin: 9 people, 52.94%
  6. Ibuprofen: 9 people, 52.94%
  7. Metronidazole: 9 people, 52.94%
  8. Cymbalta: 9 people, 52.94%
  9. Mephyton: 9 people, 52.94%
  10. Lyrica: 9 people, 52.94%

What are other side effects people have besides Hot flush? *

  1. Back Pain: 11 people, 64.71%
  2. Fatigue (feeling of tiredness): 11 people, 64.71%
  3. Depressed Mood: 10 people, 58.82%
  4. Diarrhea: 10 people, 58.82%
  5. Stress And Anxiety: 10 people, 58.82%
  6. Cardiac Disorder: 9 people, 52.94%
  7. Otitis Media Acute (rapid inflammation of the middle ear): 9 people, 52.94%
  8. Osteomyelitis (infection of bone): 9 people, 52.94%
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 52.94%
  10. Oral Pain: 9 people, 52.94%

What are the existing conditions these people have? *

  1. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 23.53%
  2. Vitamin B12 Deficiency: 1 person, 5.88%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.88%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.88%
  5. Constipation: 1 person, 5.88%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
  7. High Blood Cholesterol: 1 person, 5.88%
  8. High Blood Pressure: 1 person, 5.88%
  9. Hypothalamo-Pituitary Disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function): 1 person, 5.88%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Nortriptyline hydrochloride and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nortriptyline hydrochloride:

Hot flush treatments and more:

How severe was Hot flush and when was it recovered:

Expand to all the drugs that have ingredients of nortriptyline hydrochloride:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nortriptyline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Browse all the conditions that are associated with Hot flush:


How the study uses the data?

The study uses data from the FDA. It is based on nortriptyline hydrochloride (the active ingredients of Nortriptyline hydrochloride) and Nortriptyline hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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