Nortriptyline hydrochloride and Muscle aches - a phase IV clinical study of FDA data

Summary:

Muscle aches is reported as a side effect among people who take Nortriptyline hydrochloride (nortriptyline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Neurontin, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Muscle aches when taking Nortriptyline hydrochloride. It is created by eHealthMe based on reports of 3,475 people who have side effects when taking Nortriptyline hydrochloride from the FDA, and is updated regularly.

What is Nortriptyline hydrochloride?

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,817 Nortriptyline hydrochloride users. Check the latest studies of Nortriptyline hydrochloride.

What is Muscle aches?

Muscle aches (muscle pain) is found to be associated with 2,721 drugs and 3,741 conditions by eHealthMe. Check the latest studies of Muscle aches.

On Jul, 16, 2026

3,475 people reported to have side effects when taking Nortriptyline hydrochloride.
Among them, 37 people (1.06%) have Muscle aches.

Could Nortriptyline hydrochloride cause Muscle aches?

Among these 37 people:

How long have people been on Nortriptyline hydrochloride when they have Muscle aches? *

What is the gender of people who have Muscle aches when taking Nortriptyline hydrochloride? *

female: 65.71 %
male: 34.29 %

What is the age of people who have Muscle aches when taking Nortriptyline hydrochloride? *

What are other drugs people take besides Nortriptyline hydrochloride? *

What are other side effects people have besides Muscle aches? *

Fatigue (feeling of tiredness): 25 people, 67.57%
Stress And Anxiety: 20 people, 54.05%
Nausea (feeling of having an urge to vomit): 18 people, 48.65%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 14 people, 37.84%
Weight Decreased: 13 people, 35.14%
Hypoaesthesia (reduced sense of touch or sensation): 13 people, 35.14%
Joint Pain: 13 people, 35.14%
Back Pain: 13 people, 35.14%
Rib Fracture: 12 people, 32.43%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 12 people, 32.43%

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 10.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.41%
Myotonia (a state of hyperexcitability in muscle fibres in which a voluntary contraction): 2 people, 5.41%
Sleep Disorder: 1 person, 2.70%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 2.70%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 2.70%
Drowsiness: 1 person, 2.70%
Gastric Ulcer (stomach ulcer): 1 person, 2.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.70%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Nortriptyline hydrochloride and have Muscle aches?

- Check whether Muscle aches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nortriptyline hydrochloride:

Nortriptyline hydrochloride (4,817 reports)

Muscle aches treatments and more:

Muscle aches (219,259 reports)

Browse all side effects of Nortriptyline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle aches:

Muscle aches (2,721 drugs)

Browse all the conditions that are associated with Muscle aches:

Muscle aches (3,741 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nortriptyline hydrochloride (the active ingredients of Nortriptyline hydrochloride) and Nortriptyline hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.