Nortriptyline hydrochloride and Psychomotor hyperactivity - a phase IV clinical study of FDA data

Summary:

Psychomotor hyperactivity is reported as a side effect among people who take Nortriptyline hydrochloride (nortriptyline hydrochloride), especially for people who are male, 60+ old, also take Lamotrigine, and have Major depression.

The phase IV clinical study analyzes which people have Psychomotor hyperactivity when taking Nortriptyline hydrochloride. It is created by eHealthMe based on reports of 3,475 people who have side effects when taking Nortriptyline hydrochloride from the FDA, and is updated regularly.

What is Nortriptyline hydrochloride?

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,817 Nortriptyline hydrochloride users. Check the latest studies of Nortriptyline hydrochloride.

What is Psychomotor hyperactivity?

Psychomotor hyperactivity (feelings of extreme restlessness) is found to be associated with 889 drugs and 1,101 conditions by eHealthMe. Check the latest studies of Psychomotor hyperactivity.

On Jul, 08, 2026

3,475 people reported to have side effects when taking Nortriptyline hydrochloride.
Among them, 15 people (0.43%) have Psychomotor hyperactivity.

Could Nortriptyline hydrochloride cause Psychomotor hyperactivity?

Among these 15 people:

What is the gender of people who have Psychomotor hyperactivity when taking Nortriptyline hydrochloride? *

female: 0.0 %
male: 100 %

What is the age of people who have Psychomotor hyperactivity when taking Nortriptyline hydrochloride? *

What are other drugs people take besides Nortriptyline hydrochloride? *

Quetiapine Fumarate: 8 people, 53.33%
Lamotrigine: 8 people, 53.33%
Zopiclone: 7 people, 46.67%
Temazepam: 7 people, 46.67%
Mirtazapine: 7 people, 46.67%
Venlafaxine Hydrochloride: 5 people, 33.33%
Lithium Carbonate: 2 people, 13.33%
Remeron: 1 person, 6.67%

What are other side effects people have besides Psychomotor hyperactivity? *

Suicide Attempt: 14 people, 93.33%
Sleep Disorder: 14 people, 93.33%
Restless Leg Syndrome (a powerful urge to move your legs): 14 people, 93.33%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 14 people, 93.33%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 14 people, 93.33%
Insomnia (sleeplessness): 14 people, 93.33%
Feelings Of Worthlessness: 14 people, 93.33%
Emotional Distress: 14 people, 93.33%
Drug Intolerance (drug sensitivity): 14 people, 93.33%
Drug Ineffective: 14 people, 93.33%

What are the existing conditions these people have? *

Stress And Anxiety: 7 people, 46.67%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 7 people, 46.67%

* Approximation only. Some reports may have incomplete information.

Do you take Nortriptyline hydrochloride and have Psychomotor hyperactivity?

- Check whether Psychomotor hyperactivity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nortriptyline hydrochloride:

Nortriptyline hydrochloride (4,817 reports)

Browse all side effects of Nortriptyline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psychomotor hyperactivity:

Psychomotor hyperactivity (889 drugs)

Browse all the conditions that are associated with Psychomotor hyperactivity:

Psychomotor hyperactivity (1,101 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nortriptyline hydrochloride (the active ingredients of Nortriptyline hydrochloride) and Nortriptyline hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.