Nortriptyline hydrochloride and Suicidal ideation - a phase IV clinical study of FDA data

Summary:

Suicidal ideation is reported as a side effect among people who take Nortriptyline hydrochloride (nortriptyline hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Cymbalta, and have Panic disorder.

The phase IV clinical study analyzes which people have Suicidal ideation when taking Nortriptyline hydrochloride. It is created by eHealthMe based on reports of 3,475 people who have side effects when taking Nortriptyline hydrochloride from the FDA, and is updated regularly.

What is Nortriptyline hydrochloride?

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,817 Nortriptyline hydrochloride users. Check the latest studies of Nortriptyline hydrochloride.

What is Suicidal ideation?

Suicidal ideation is found to be associated with 1,980 drugs and 2,341 conditions by eHealthMe. Check the latest studies of Suicidal ideation.

On Jul, 22, 2026

3,475 people reported to have side effects when taking Nortriptyline hydrochloride.
Among them, 57 people (1.64%) have Suicidal ideation.

Could Nortriptyline hydrochloride cause Suicidal ideation?

Among these 57 people:

How long have people been on Nortriptyline hydrochloride when they have Suicidal ideation? *

What is the gender of people who have Suicidal ideation when taking Nortriptyline hydrochloride? *

female: 86.79 %
male: 13.21 %

What is the age of people who have Suicidal ideation when taking Nortriptyline hydrochloride? *

What are other drugs people take besides Nortriptyline hydrochloride? *

Cymbalta: 25 people, 43.86%
Viibryd: 18 people, 31.58%
Luvox: 17 people, 29.82%
Diazepam: 12 people, 21.05%
Venlafaxine Hydrochloride: 10 people, 17.54%
Vortioxetine Hydrobromide: 10 people, 17.54%
Quetiapine Fumarate: 9 people, 15.79%
Mirtazapine: 9 people, 15.79%
Paroxetine Hydrochloride: 8 people, 14.04%
Vitamin C: 8 people, 14.04%

What are other side effects people have besides Suicidal ideation? *

Weight Increased: 24 people, 42.11%
Stress And Anxiety: 24 people, 42.11%
Fever: 22 people, 38.60%
High Blood Pressure: 21 people, 36.84%
Anger: 20 people, 35.09%
Rashes (redness): 20 people, 35.09%
Abdominal Discomfort: 19 people, 33.33%
Tremor (trembling or shaking movements in one or more parts of your body): 18 people, 31.58%
Ocular Discomfort (a generic expression when there is lack of ease in/about the eyes): 17 people, 29.82%
Agitation (state of anxiety or nervous excitement): 17 people, 29.82%

What are the existing conditions these people have? *

Panic Disorder: 20 people, 35.09%
Stress And Anxiety: 18 people, 31.58%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 10.53%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 10.53%
Drowsiness: 4 people, 7.02%
Bipolar Disorder (mood disorder): 4 people, 7.02%
Lung Carcinoma Cell Type Unspecified Stage I (the lung cancer is small and hasn't spread to the lymph nodes): 3 people, 5.26%
Metastases To Bone (cancer spreads to bone): 3 people, 5.26%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 3 people, 5.26%
Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Nortriptyline hydrochloride and have Suicidal ideation?

- Check whether Suicidal ideation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nortriptyline hydrochloride:

Nortriptyline hydrochloride (4,817 reports)

Suicidal ideation treatments and more:

Suicidal ideation (109,012 reports)

Browse all side effects of Nortriptyline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Suicidal ideation:

Suicidal ideation (1,980 drugs)

Browse all the conditions that are associated with Suicidal ideation:

Suicidal ideation (2,341 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nortriptyline hydrochloride (the active ingredients of Nortriptyline hydrochloride) and Nortriptyline hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.