Norvir and Multi-organ failure - a phase IV clinical study of FDA data

Summary:

Multi-organ failure is reported as a side effect among people who take Norvir (ritonavir), especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months also take Isentress, and have Cytomegalovirus infection.

The phase IV clinical study analyzes which people have Multi-organ failure when taking Norvir. It is created by eHealthMe based on reports of 24,715 people who have side effects when taking Norvir from the FDA, and is updated regularly.

What is Norvir?

Norvir has active ingredients of ritonavir. It is often used in hiv infection. eHealthMe is studying from 24,973 Norvir users. Check the latest studies of Norvir.

What is Multi-organ failure?

Multi-organ failure (multisystem organ failure) is found to be associated with 1,380 drugs and 2,281 conditions by eHealthMe. Check the latest studies of Multi-organ failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

24,715 people reported to have side effects when taking Norvir.
Among them, 97 people (0.39%) have Multi-organ failure.

Could Norvir cause Multi-organ failure?

Among these 97 people:

How long have people been on Norvir when they have Multi-organ failure? *

  • < 1 month: 20.45 %
  • 1 - 6 months: 43.18 %
  • 6 - 12 months: 27.27 %
  • 1 - 2 years: 6.82 %
  • 2 - 5 years: 2.27 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Multi-organ failure when taking Norvir? *

  • female: 41.67 %
  • male: 58.33 %

What is the age of people who have Multi-organ failure when taking Norvir? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.44 %
  • 30-39: 25.61 %
  • 40-49: 31.71 %
  • 50-59: 25.61 %
  • 60+: 14.63 %

What are other drugs people take besides Norvir? *

  1. Isentress: 29 people, 29.90%
  2. Reyataz: 24 people, 24.74%
  3. Truvada: 19 people, 19.59%
  4. Prezista: 18 people, 18.56%
  5. Viread: 18 people, 18.56%
  6. Videx: 16 people, 16.49%
  7. Zithromax: 10 people, 10.31%
  8. Stavudine: 10 people, 10.31%
  9. Fortovase: 10 people, 10.31%
  10. Bactrim: 9 people, 9.28%

What are other side effects people have besides Multi-organ failure? *

  1. Acute Kidney Failure: 26 people, 26.80%
  2. Lactic Acidosis (low ph in body tissues): 22 people, 22.68%
  3. Hepatic Failure (liver failure): 19 people, 19.59%
  4. Fever: 18 people, 18.56%
  5. Cytolytic Hepatitis (dissolution or destruction of a liver cell): 10 people, 10.31%
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 10 people, 10.31%
  7. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 10 people, 10.31%
  8. Hepatitis Cholestatic (flow of bile from the liver is slowed or blocked): 9 people, 9.28%
  9. Septic Shock (shock due to blood infection): 9 people, 9.28%
  10. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 8 people, 8.25%

What are the existing conditions these people have? *

  1. Cytomegalovirus Infection: 9 people, 9.28%
  2. Prurigo (chronic skin disease causing severe itching): 8 people, 8.25%
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 8 people, 8.25%
  4. Insomnia (sleeplessness): 8 people, 8.25%
  5. Hepatitis C: 7 people, 7.22%
  6. Angioimmunoblastic T-Cell Lymphoma (mature t-cell cancer of the blood or lymph vessel): 3 people, 3.09%
  7. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 3 people, 3.09%
  8. Fever: 3 people, 3.09%
  9. Pneumonia Fungal: 3 people, 3.09%
  10. Gastritis (inflammation of stomach): 3 people, 3.09%

* Approximation only. Some reports may have incomplete information.

Do you take Norvir and have Multi-organ failure?

- Check whether Multi-organ failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norvir:

Multi-organ failure treatments and more:

How severe was Multi-organ failure and when was it recovered:

Expand to all the drugs that have ingredients of ritonavir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norvir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multi-organ failure:

Browse all the conditions that are associated with Multi-organ failure:


How the study uses the data?

The study uses data from the FDA. It is based on ritonavir (the active ingredients of Norvir) and Norvir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: