Nourianz and Thinking abnormal - a phase IV clinical study of FDA data

Summary:

Thinking abnormal is reported as a side effect among people who take Nourianz (istradefylline), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Sinemet, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Thinking abnormal when taking Nourianz. It is created by eHealthMe based on reports of 5,258 people who have side effects when taking Nourianz from the FDA, and is updated regularly.

What is Nourianz?

Nourianz has active ingredients of istradefylline. eHealthMe is studying from 5,260 Nourianz users. Check the latest studies of Nourianz.

What is Thinking abnormal?

Thinking abnormal is found to be associated with 1,062 drugs and 1,183 conditions by eHealthMe. Check the latest studies of Thinking abnormal.



On Jul, 03, 2026

5,258 people reported to have side effects when taking Nourianz.
Among them, 14 people (0.27%) have Thinking abnormal.

Could Nourianz cause Thinking abnormal?

Among these 14 people:

How long have people been on Nourianz when they have Thinking abnormal? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Thinking abnormal when taking Nourianz? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Thinking abnormal when taking Nourianz? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Nourianz? *

  1. Sinemet: 4 people, 28.57%
  2. Zantac: 3 people, 21.43%
  3. Stivarga: 3 people, 21.43%
  4. Zofran: 3 people, 21.43%
  5. Miralax: 2 people, 14.29%
  6. Omeprazole: 2 people, 14.29%
  7. Amlodipine: 2 people, 14.29%
  8. Comtan: 2 people, 14.29%
  9. Donepezil: 2 people, 14.29%
  10. Estradiol: 2 people, 14.29%

What are other side effects people have besides Thinking abnormal? *

  1. Weight Decreased: 5 people, 35.71%
  2. Fall: 5 people, 35.71%
  3. Hoarseness Or Changing Voice: 5 people, 35.71%
  4. Dyskinesia (abnormality or impairment of voluntary movement): 5 people, 35.71%
  5. Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 28.57%
  6. Nausea And Vomiting: 4 people, 28.57%
  7. Nausea (feeling of having an urge to vomit): 4 people, 28.57%
  8. Hallucinations (sensations that appear real but are created by your mind): 4 people, 28.57%
  9. Muscle Spasms (muscle contraction): 3 people, 21.43%
  10. Nasopharyngitis (inflammation of the nasopharynx): 3 people, 21.43%

What are the existing conditions these people have? *

  1. Parkinson's Disease: 10 people, 71.43%
  2. On And Off Phenomenon: 2 people, 14.29%
  3. Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 14.29%
  4. Constipation: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Nourianz and have Thinking abnormal?

- Check whether Thinking abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nourianz:

Thinking abnormal treatments and more:

How severe was Thinking abnormal and when was it recovered:

Expand to all the drugs that have ingredients of istradefylline:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nourianz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thinking abnormal:

Browse all the conditions that are associated with Thinking abnormal:


How the study uses the data?

The study uses data from the FDA. It is based on istradefylline (the active ingredients of Nourianz) and Nourianz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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