Novalgin and Mucosal erosion - a phase IV clinical study of FDA data

Summary:

Mucosal erosion is reported as a side effect among people who take Novalgin (metamizole), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Plavix, and have Electrolyte depletion.

The phase IV clinical study analyzes which people have Mucosal erosion when taking Novalgin. It is created by eHealthMe based on reports of 10,087 people who have side effects when taking Novalgin from the FDA, and is updated regularly.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.

What is Mucosal erosion?

Mucosal erosion (peeling off of mucous membrane) is found to be associated with 211 drugs and 400 conditions by eHealthMe. Check the latest studies of Mucosal erosion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

10,087 people reported to have side effects when taking Novalgin.
Among them, 23 people (0.23%) have Mucosal erosion.

Among these 23 people:

How long have people been on Novalgin when they have Mucosal erosion? *

What is the gender of people who have Mucosal erosion when taking Novalgin? *

female: 100 %
male: 0.0 %

What is the age of people who have Mucosal erosion when taking Novalgin? *

What are other drugs people take besides Novalgin? *

Cotrim: 22 people, 95.65%
Vioxx: 22 people, 95.65%
Plavix: 22 people, 95.65%
Aspirin: 17 people, 73.91%
Diazepam: 17 people, 73.91%
Torsemide: 17 people, 73.91%
Clemastine Fumarate: 17 people, 73.91%
Isosorbide Mononitrate: 17 people, 73.91%
Glyburide: 17 people, 73.91%
Calcium: 16 people, 69.57%

What are other side effects people have besides Mucosal erosion? *

Erythema Multiforme (a type of hypersensitivity reaction): 23 people, 100.00%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 23 people, 100.00%
Mouth Ulcers: 22 people, 95.65%
Conjunctivitis (pink eye): 22 people, 95.65%
Rashes (redness): 17 people, 73.91%
Genital Erosion (ulcer on genital): 8 people, 34.78%
Generalised Erythema (redness of the skin all over the body): 5 people, 21.74%
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 1 person, 4.35%
Pruritus Generalised (generalized itching): 1 person, 4.35%
Oral Mucosa Erosion (erosion of mouth mucous membrane): 1 person, 4.35%

What are the existing conditions these people have? *

Heart Disease: 22 people, 95.65%
Local Anaesthesia: 22 people, 95.65%
Urinary Tract Infection: 22 people, 95.65%
Bleeding Disorders: 22 people, 95.65%
Stable Angina (a constant chest pain): 22 people, 95.65%
Cardiac Failure: 22 people, 95.65%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 22 people, 95.65%
Pemphigoid (tense blisters on the skin): 22 people, 95.65%
Osteoporosis (bones weak and more likely to break): 22 people, 95.65%
Electrolyte Depletion (act of decreasing electrolyte markedly): 22 people, 95.65%

* Approximation only. Some reports may have incomplete information.

Do you take Novalgin and have Mucosal erosion?

- Check whether Mucosal erosion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Novalgin:

Novalgin (10,177 reports)

Mucosal erosion treatments and more:

Mucosal erosion (1,167 reports)

Browse all side effects of Novalgin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mucosal erosion:

Mucosal erosion (211 drugs)

Browse all the conditions that are associated with Mucosal erosion:

Mucosal erosion (400 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metamizole (the active ingredients of Novalgin) and Novalgin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.