Novalgin and Tenosynovitis - a phase IV clinical study of FDA data

Summary:

Tenosynovitis is reported as a side effect among people who take Novalgin (metamizole), especially for people who are female, 50-59 old, also take Gilenya, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Tenosynovitis when taking Novalgin. It is created by eHealthMe based on reports of 10,087 people who have side effects when taking Novalgin from the FDA, and is updated regularly.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.

What is Tenosynovitis?

Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon) is found to be associated with 457 drugs and 490 conditions by eHealthMe. Check the latest studies of Tenosynovitis.

On Jul, 13, 2026

10,087 people reported to have side effects when taking Novalgin.
Among them, 11 people (0.11%) have Tenosynovitis.

Among these 11 people:

What is the gender of people who have Tenosynovitis when taking Novalgin? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Tenosynovitis when taking Novalgin? *

What are other drugs people take besides Novalgin? *

Lemtrada: 2 people, 18.18%
Humira: 2 people, 18.18%
Gilenya: 2 people, 18.18%
Lyrica: 1 person, 9.09%

What are other side effects people have besides Tenosynovitis? *

Anaemia (lack of blood): 2 people, 18.18%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 18.18%
Duodenal Perforation (complication of duodenal ulcer): 2 people, 18.18%
Migraine (headache): 2 people, 18.18%
Diverticulum Intestinal (a pouch that is attached to the first part of the small intestine): 2 people, 18.18%
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 2 people, 18.18%
Hypochromic Anaemia (hypochromic anaemia is a generic term for any type of anaemia in which the red blood cells (erythrocytes) are paler than normal): 2 people, 18.18%
Hyperthyroidism (over activity of the thyroid gland): 2 people, 18.18%
Skin Exfoliation (removal of the oldest dead skin cells): 2 people, 18.18%
Tension Headache: 2 people, 18.18%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 63.64%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 18.18%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 9.09%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Novalgin and have Tenosynovitis?

- Check whether Tenosynovitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Novalgin:

Novalgin (10,177 reports)

Tenosynovitis treatments and more:

Tenosynovitis (4,673 reports)

Browse all side effects of Novalgin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tenosynovitis:

Tenosynovitis (457 drugs)

Browse all the conditions that are associated with Tenosynovitis:

Tenosynovitis (490 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metamizole (the active ingredients of Novalgin) and Novalgin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.