Novantrone and Enterococcal infection - a phase IV clinical study of FDA data

Summary:

Enterococcal infection is reported as a side effect among people who take Novantrone (mitoxantrone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cytarabine, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Enterococcal infection when taking Novantrone. It is created by eHealthMe based on reports of 3,338 people who have side effects when taking Novantrone from the FDA, and is updated regularly.

What is Novantrone?

Novantrone has active ingredients of mitoxantrone hydrochloride. It is often used in multiple sclerosis. eHealthMe is studying from 3,349 Novantrone users. Check the latest studies of Novantrone.

What is Enterococcal infection?

Enterococcal infection is found to be associated with 624 drugs and 760 conditions by eHealthMe. Check the latest studies of Enterococcal infection.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

3,338 people reported to have side effects when taking Novantrone.
Among them, 20 people (0.6%) have Enterococcal infection.

Could Novantrone cause Enterococcal infection?

Among these 20 people:

How long have people been on Novantrone when they have Enterococcal infection? *

What is the gender of people who have Enterococcal infection when taking Novantrone? *

female: 30 %
male: 70 %

What is the age of people who have Enterococcal infection when taking Novantrone? *

What are other drugs people take besides Novantrone? *

What are other side effects people have besides Enterococcal infection? *

Febrile Neutropenia (fever with reduced white blood cells): 8 people, 40.00%
Pneumonia: 6 people, 30.00%
Acute Kidney Failure: 4 people, 20.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 20.00%
Pleural Effusion (water on the lungs): 4 people, 20.00%
Pulmonary Oedema (fluid accumulation in the lungs): 4 people, 20.00%
Atelectasis (partial or complete collapse of the lung): 4 people, 20.00%
High Blood Pressure: 4 people, 20.00%
Clostridial Infection (infectious conditions by clostridium bacteria): 3 people, 15.00%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 3 people, 15.00%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 14 people, 70.00%
Acute Leukaemia (blood cancer): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Novantrone and have Enterococcal infection?

- Check whether Enterococcal infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Novantrone:

Novantrone (3,349 reports)

Browse all side effects of Novantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enterococcal infection:

Enterococcal infection (624 drugs)

Browse all the conditions that are associated with Enterococcal infection:

Enterococcal infection (760 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mitoxantrone hydrochloride (the active ingredients of Novantrone) and Novantrone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.