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Novothyrox and Epilepsy - a phase IV clinical study of FDA data

Summary:

Epilepsy is reported as a side effect among people who take Novothyrox (levothyroxine sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Calcium, and have Post procedural hypothyroidism.

The phase IV clinical study analyzes which people have Epilepsy when taking Novothyrox. It is created by eHealthMe based on reports of 11,309 people who have side effects when taking Novothyrox from the FDA, and is updated regularly.

What is Novothyrox?

Novothyrox has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 11,364 Novothyrox users. Check the latest studies of Novothyrox.

What is Epilepsy?

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures) is found to be associated with 1,163 drugs and 1,777 conditions by eHealthMe. Check the latest studies of Epilepsy.

On Jul, 31, 2026

11,309 people reported to have side effects when taking Novothyrox.
Among them, 22 people (0.19%) have Epilepsy.

Could Novothyrox cause Epilepsy?

Among these 22 people:

How long have people been on Novothyrox when they have Epilepsy? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Epilepsy when taking Novothyrox? *

  • female: 90 %
  • male: 10 %

What is the age of people who have Epilepsy when taking Novothyrox? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.67 %
  • 20-29: 13.33 %
  • 30-39: 13.33 %
  • 40-49: 20.0 %
  • 50-59: 20.0 %
  • 60+: 26.67 %

What are other drugs people take besides Novothyrox? *

  1. Magnesium: 1 person, 4.55%
  2. Calcium: 1 person, 4.55%

What are other side effects people have besides Epilepsy? *

  1. Fatigue (feeling of tiredness): 10 people, 45.45%
  2. Muscle Aches (muscle pain): 6 people, 27.27%
  3. Insomnia (sleeplessness): 5 people, 22.73%
  4. Weakness: 5 people, 22.73%
  5. Dizziness: 4 people, 18.18%
  6. Hair Loss: 4 people, 18.18%
  7. Migraine (headache): 4 people, 18.18%
  8. Middle Insomnia (difficulty returning to sleep after awakening either in the middle of the night): 3 people, 13.64%
  9. Blood Thyroid Stimulating Hormone Increased: 3 people, 13.64%
  10. Memory Loss: 3 people, 13.64%

What are the existing conditions these people have? *

  1. Post Procedural Hypothyroidism: 2 people, 9.09%
  2. Thyroid Diseases: 1 person, 4.55%
  3. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 1 person, 4.55%
  4. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Novothyrox and have Epilepsy?

- Check whether Epilepsy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Novothyrox:

Epilepsy treatments and more:

How severe was Epilepsy and when was it recovered:

Expand to all the drugs that have ingredients of levothyroxine sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Novothyrox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epilepsy:

Browse all the conditions that are associated with Epilepsy:

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Novothyrox) and Novothyrox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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