Nph insulin and Arrhythmias - a phase IV clinical study of FDA data

Summary:

Arrhythmias is reported as a side effect among people who take Nph insulin (insulin susp isophane beef), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have High blood pressure.

The phase IV clinical study analyzes which people have Arrhythmias when taking Nph insulin. It is created by eHealthMe based on reports of 1,834 people who have side effects when taking Nph insulin from the FDA, and is updated regularly.

What is Nph insulin?

Nph insulin has active ingredients of insulin susp isophane beef. It is often used in diabetes. eHealthMe is studying from 1,871 Nph insulin users. Check the latest studies of Nph insulin.

What is Arrhythmias?

Arrhythmias (irregular heartbeat) is found to be associated with 2,759 drugs and 4,837 conditions by eHealthMe. Check the latest studies of Arrhythmias.



On Jul, 07, 2026

1,834 people reported to have side effects when taking Nph insulin.
Among them, 25 people (1.36%) have Arrhythmias.

Could Nph insulin cause Arrhythmias?

Among these 25 people:

How long have people been on Nph insulin when they have Arrhythmias? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Arrhythmias when taking Nph insulin? *

  • female: 60 %
  • male: 40 %

What is the age of people who have Arrhythmias when taking Nph insulin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 8 %
  • 40-49: 16 %
  • 50-59: 36 %
  • 60+: 40 %

What are other drugs people take besides Nph insulin? *

  1. Metformin: 10 people, 40.00%
  2. Pantoprazole: 7 people, 28.00%
  3. Sertraline: 6 people, 24.00%
  4. Oxycodone: 5 people, 20.00%
  5. Prednisone: 5 people, 20.00%
  6. Fluconazole: 4 people, 16.00%
  7. Morphine Sulfate: 4 people, 16.00%
  8. Methotrexate: 4 people, 16.00%
  9. Lorazepam: 4 people, 16.00%
  10. Lidocaine: 4 people, 16.00%

What are other side effects people have besides Arrhythmias? *

  1. Dyspnea (difficult or laboured breathing): 10 people, 40.00%
  2. Fever: 10 people, 40.00%
  3. Malaise (a feeling of general discomfort or uneasiness): 7 people, 28.00%
  4. Headache (pain in head): 6 people, 24.00%
  5. Pneumonia: 6 people, 24.00%
  6. Pain In Extremity: 6 people, 24.00%
  7. Pain: 6 people, 24.00%
  8. Hypersensitivity: 6 people, 24.00%
  9. Fatigue (feeling of tiredness): 5 people, 20.00%
  10. Hypotension (abnormally low blood pressure): 5 people, 20.00%

What are the existing conditions these people have? *

  1. High Blood Pressure: 10 people, 40.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 24.00%
  3. Thyroid Diseases: 6 people, 24.00%
  4. High Blood Cholesterol: 3 people, 12.00%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 12.00%
  6. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 12.00%
  7. Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 3 people, 12.00%
  8. Blood Glucose Increased: 2 people, 8.00%
  9. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 8.00%
  10. Depression: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Nph insulin and have Arrhythmias?

- Check whether Arrhythmias is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nph insulin:

Arrhythmias treatments and more:

How severe was Arrhythmias and when was it recovered:

Expand to all the drugs that have ingredients of insulin susp isophane beef:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nph insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arrhythmias:

Browse all the conditions that are associated with Arrhythmias:


How the study uses the data?

The study uses data from the FDA. It is based on insulin susp isophane beef (the active ingredients of Nph insulin) and Nph insulin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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