Nplate and Aortic stenosis - a phase IV clinical study of FDA data

Summary:

Aortic stenosis is reported as a side effect among people who take Nplate (romiplostim), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Flunisolide, and have Idiopathic thrombocytopenic purpura.

The phase IV clinical study analyzes which people have Aortic stenosis when taking Nplate. It is created by eHealthMe based on reports of 17,818 people who have side effects when taking Nplate from the FDA, and is updated regularly.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.

What is Aortic stenosis?

Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta) is found to be associated with 779 drugs and 970 conditions by eHealthMe. Check the latest studies of Aortic stenosis.

On Aug, 07, 2026

17,818 people reported to have side effects when taking Nplate.
Among them, 19 people (0.11%) have Aortic stenosis.

Among these 19 people:

How long have people been on Nplate when they have Aortic stenosis? *

What is the gender of people who have Aortic stenosis when taking Nplate? *

female: 70.59 %
male: 29.41 %

What is the age of people who have Aortic stenosis when taking Nplate? *

What are other drugs people take besides Nplate? *

What are other side effects people have besides Aortic stenosis? *

Thrombocytopenia (decrease of platelets in blood): 7 people, 36.84%
Haemorrhage (bleeding): 6 people, 31.58%
Drug Ineffective: 4 people, 21.05%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 15.79%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 15.79%
Cardiac Disorder: 3 people, 15.79%
Blast Cell Count Increased: 3 people, 15.79%
Aortic Arteriosclerosis (hardening of the aortic arteries): 2 people, 10.53%
Right Ventricular Dysfunction: 2 people, 10.53%
Cardiac Failure Congestive: 2 people, 10.53%

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 15 people, 78.95%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.26%
Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 5.26%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Nplate and have Aortic stenosis?

- Check whether Aortic stenosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nplate:

Nplate (17,850 reports)

Aortic stenosis treatments and more:

Aortic stenosis (8,138 reports)

Browse all side effects of Nplate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic stenosis:

Aortic stenosis (779 drugs)

Browse all the conditions that are associated with Aortic stenosis:

Aortic stenosis (970 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on romiplostim (the active ingredients of Nplate) and Nplate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.