Nplate and Cachexia - a phase IV clinical study of FDA data
Summary:
Cachexia is reported as a side effect among people who take Nplate (romiplostim), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Neupogen, and have Idiopathic thrombocytopenic purpura.
The phase IV clinical study analyzes which people have Cachexia when taking Nplate. It is created by eHealthMe based on reports of 17,818 people who have side effects when taking Nplate from the FDA, and is updated regularly.
What is Nplate?
Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.
What is Cachexia?
Cachexia (loss of weight) is found to be associated with 682 drugs and 1,199 conditions by eHealthMe. Check the latest studies of Cachexia.
17,818 people reported to have side effects when taking Nplate.
Among them, 11 people (0.06%) have Cachexia.

Among these 11 people:
How long have people been on Nplate when they have Cachexia? *
- < 1 month: 50 %
- 1 - 6 months: 40 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 10 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Cachexia when taking Nplate? *
- female: 90 %
- male: 10 %
What is the age of people who have Cachexia when taking Nplate? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 50 %
- 60+: 50 %
What are other drugs people take besides Nplate? *
- Neupogen: 5 people, 45.45%
- Metoprolol Tartrate: 4 people, 36.36%
- Zyprexa: 3 people, 27.27%
- Prilosec: 3 people, 27.27%
- Cyclophosphamide: 3 people, 27.27%
- Cytarabine: 3 people, 27.27%
- Dexamethasone: 3 people, 27.27%
- Methotrexate: 3 people, 27.27%
- Allopurinol: 3 people, 27.27%
- Valtrex: 3 people, 27.27%
What are other side effects people have besides Cachexia? *
- Weight Decreased: 5 people, 45.45%
- Breast Cancer Metastatic: 4 people, 36.36%
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 4 people, 36.36%
- Leukocytosis (increased white blood cells): 3 people, 27.27%
- Infection: 3 people, 27.27%
- Head Injury: 3 people, 27.27%
- Oedema (fluid collection in tissue): 3 people, 27.27%
- Weakness: 3 people, 27.27%
- Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 27.27%
- Thrombocytopenia (decrease of platelets in blood): 3 people, 27.27%
What are the existing conditions these people have? *
- Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 6 people, 54.55%
- Thrombocytopenia (decrease of platelets in blood): 3 people, 27.27%
- Pain: 3 people, 27.27%
- Sleep Disorder: 1 person, 9.09%
- Constipation: 1 person, 9.09%
- Chest Pain: 1 person, 9.09%
- Carcinoid Tumor: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Nplate and have Cachexia?
- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Nplate:
- Nplate (17,850 reports)
Cachexia treatments and more:
- Cachexia (7,763 reports)
How severe was Cachexia and when was it recovered:
Expand to all the drugs that have ingredients of romiplostim:
- Cachexia and drugs with ingredients of romiplostim (12 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nplate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Cachexia:
- Cachexia (682 drugs)
Browse all the conditions that are associated with Cachexia:
- Cachexia (1,199 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on romiplostim (the active ingredients of Nplate) and Nplate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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