Nucynta er and Adverse event - a phase IV clinical study of FDA data

Summary:

Adverse event is reported as a side effect among people who take Nucynta er (tapentadol hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Nucynta, and have Sleep disorder.

The phase IV clinical study analyzes which people have Adverse event when taking Nucynta er. It is created by eHealthMe based on reports of 2,418 people who have side effects when taking Nucynta er from the FDA, and is updated regularly.

What is Nucynta er?

Nucynta er has active ingredients of tapentadol hydrochloride. It is often used in pain. eHealthMe is studying from 2,508 Nucynta er users. Check the latest studies of Nucynta er.

What is Adverse event?

Adverse event is found to be associated with 1,690 drugs and 1,662 conditions by eHealthMe. Check the latest studies of Adverse event.

On Jul, 04, 2026

2,418 people reported to have side effects when taking Nucynta er.
Among them, 68 people (2.81%) have Adverse event.

Among these 68 people:

How long have people been on Nucynta er when they have Adverse event? *

What is the gender of people who have Adverse event when taking Nucynta er? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Adverse event when taking Nucynta er? *

What are other drugs people take besides Nucynta er? *

What are other side effects people have besides Adverse event? *

Drug Ineffective: 13 people, 19.12%
Dizziness: 8 people, 11.76%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 7 people, 10.29%
Tremor (trembling or shaking movements in one or more parts of your body): 7 people, 10.29%
Drug Administration Error: 5 people, 7.35%
High Blood Pressure: 5 people, 7.35%
Gait Disturbance: 5 people, 7.35%
Chest Pain: 5 people, 7.35%
Poor Quality Sleep: 5 people, 7.35%
Feeling Hot: 5 people, 7.35%

What are the existing conditions these people have? *

Sleep Disorder: 8 people, 11.76%
Gastric Disorder (disease of stomach): 7 people, 10.29%
Swelling: 5 people, 7.35%
Muscle Spasms (muscle contraction): 5 people, 7.35%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 4.41%
Neuropathy Peripheral (surface nerve damage): 3 people, 4.41%
Depression: 3 people, 4.41%
Breakthrough Pain: 2 people, 2.94%
Migraine (headache): 2 people, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Nucynta er and have Adverse event?

- Check whether Adverse event is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nucynta er:

Nucynta er (2,508 reports)

Adverse event treatments and more:

Adverse event (100,133 reports)

Browse all side effects of Nucynta er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adverse event:

Adverse event (1,690 drugs)

Browse all the conditions that are associated with Adverse event:

Adverse event (1,662 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tapentadol hydrochloride (the active ingredients of Nucynta er) and Nucynta er (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.