Nuvaring and Intra-uterine death - a phase IV clinical study of FDA data

Summary:

Intra-uterine death is reported as a side effect among people who take Nuvaring (ethinyl estradiol; etonogestrel), especially for people who are 20-29 old, have been taking the drug for 1 - 6 months also take Clindesse, and have Sinusitis.

The study is created by eHealthMe based on reports of 27,664 people who have side effects when taking Nuvaring from the FDA, and is updated regularly.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

On Jul, 10, 2026

27,664 people reported to have side effects when taking Nuvaring.
Among them, 38 people (0.14%) died.

Could Nuvaring cause Intra-uterine death?

Among these 38 people:

How long have people been on Nuvaring when they died? *

What is the age of people who died when taking Nuvaring? *

What are other drugs people take besides Nuvaring? *

What are other side effects people have before they died? *

Drug Exposure During Pregnancy: 18 people, 47.37%
Pulmonary Embolism (blockage of the main artery of the lung): 15 people, 39.47%
Pregnancy With Contraceptive Device: 12 people, 31.58%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 11 people, 28.95%
Abortion Spontaneous (naturally occurring miscarriage): 9 people, 23.68%
Migraine (headache): 8 people, 21.05%
Loss Of Consciousness: 7 people, 18.42%
Abortion Missed (delayed or silent miscarriage): 7 people, 18.42%
Vaginitis Bacterial (inflammation of the vagina caused by bacterial infection): 6 people, 15.79%
Drug Exposure Before Pregnancy: 6 people, 15.79%

What are the existing conditions these people have? *

Sinusitis (inflammation of sinus): 2 people, 5.26%
Weight Increased: 1 person, 2.63%
Vaginitis Bacterial (inflammation of the vagina caused by bacterial infection): 1 person, 2.63%
Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 2.63%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 2.63%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.63%
Migraine (headache): 1 person, 2.63%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 2.63%
High Blood Pressure: 1 person, 2.63%
Drug Exposure During Pregnancy: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nuvaring:

Nuvaring (28,730 reports)

Expand to all the drugs that have ingredients of ethinyl estradiol; etonogestrel:

Intra-uterine death and drugs with ingredients of ethinyl estradiol; etonogestrel (38 reports)

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nuvaring:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intra-uterine death:

Intra-uterine death (216 drugs)

Browse all the conditions that are associated with Intra-uterine death:

Intra-uterine death (412 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; etonogestrel (the active ingredients of Nuvaring) and Nuvaring (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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