Nuvaring and Oedema - a phase IV clinical study of FDA data

Summary:

Oedema is reported as a side effect among people who take Nuvaring (ethinyl estradiol; etonogestrel), especially for people who are female, 20-29 old, have been taking the drug for 1 - 6 months also take Singulair, and have Narcolepsy.

The phase IV clinical study analyzes which people have Oedema when taking Nuvaring. It is created by eHealthMe based on reports of 27,664 people who have side effects when taking Nuvaring from the FDA, and is updated regularly.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

What is Oedema?

Oedema (fluid collection in tissue) is found to be associated with 2,215 drugs and 2,311 conditions by eHealthMe. Check the latest studies of Oedema.

On Jul, 14, 2026

27,664 people reported to have side effects when taking Nuvaring.
Among them, 70 people (0.25%) have Oedema.

Among these 70 people:

How long have people been on Nuvaring when they have Oedema? *

What is the gender of people who have Oedema when taking Nuvaring? *

female: 98.53 %
male: 1.47 %

What is the age of people who have Oedema when taking Nuvaring? *

What are other drugs people take besides Nuvaring? *

What are other side effects people have besides Oedema? *

Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 31 people, 44.29%
Nausea (feeling of having an urge to vomit): 24 people, 34.29%
Migraine (headache): 24 people, 34.29%
Stress And Anxiety: 24 people, 34.29%
Pulmonary Embolism (blockage of the main artery of the lung): 22 people, 31.43%
Headache (pain in head): 20 people, 28.57%
Dizziness: 18 people, 25.71%
Pain: 16 people, 22.86%
Hypercoagulation (increased tendency for clotting of the blood): 16 people, 22.86%
Depression: 15 people, 21.43%

What are the existing conditions these people have? *

Pain: 6 people, 8.57%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 8.57%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 8.57%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 5.71%
Pneumonia: 3 people, 4.29%
Menstruation Irregular: 3 people, 4.29%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 2.86%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 2 people, 2.86%
Premenstrual Syndrome: 2 people, 2.86%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Nuvaring and have Oedema?

- Check whether Oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nuvaring:

Nuvaring (28,730 reports)

Oedema treatments and more:

Oedema (78,747 reports)

How severe was Oedema and when was it recovered:

Oedema in Nuvaring

Expand to all the drugs that have ingredients of ethinyl estradiol; etonogestrel:

Oedema and drugs with ingredients of ethinyl estradiol; etonogestrel (71 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nuvaring:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema:

Oedema (2,215 drugs)

Browse all the conditions that are associated with Oedema:

Oedema (2,311 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; etonogestrel (the active ingredients of Nuvaring) and Nuvaring (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.