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Olanzapine and Angle closure glaucoma - a phase IV clinical study of FDA data

Summary:

Angle closure glaucoma is reported as a side effect among people who take Olanzapine (olanzapine), especially for people who are male, 60+ old, also take Luvox, and have Dementia alzheimer's type.

The phase IV clinical study analyzes which people have Angle closure glaucoma when taking Olanzapine. It is created by eHealthMe based on reports of 68,588 people who have side effects when taking Olanzapine from the FDA, and is updated regularly.

What is Olanzapine?

Olanzapine has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 69,242 Olanzapine users. Check the latest studies of Olanzapine.

What is Angle closure glaucoma?

Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity) is found to be associated with 206 drugs and 481 conditions by eHealthMe. Check the latest studies of Angle closure glaucoma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

68,588 people reported to have side effects when taking Olanzapine.
Among them, 30 people (0.04%) have Angle closure glaucoma.

Could Olanzapine cause Angle closure glaucoma?

Among these 30 people:

What is the gender of people who have Angle closure glaucoma when taking Olanzapine? *

  • female: 29.17 %
  • male: 70.83 %

What is the age of people who have Angle closure glaucoma when taking Olanzapine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 8.33 %
  • 50-59: 33.33 %
  • 60+: 45.83 %

What are other drugs people take besides Olanzapine? *

  1. Topamax: 2 people, 6.67%
  2. Luvox: 2 people, 6.67%
  3. Travoprost: 1 person, 3.33%
  4. Topiramate: 1 person, 3.33%
  5. Telmisartan: 1 person, 3.33%
  6. Spironolactone: 1 person, 3.33%
  7. Paroxetine Hydrochloride: 1 person, 3.33%
  8. Lisinopril: 1 person, 3.33%
  9. Ibuprofen: 1 person, 3.33%
  10. Gentamicin Sulfate: 1 person, 3.33%

What are other side effects people have besides Angle closure glaucoma? *

  1. Blindness: 2 people, 6.67%
  2. Visual Impairment: 1 person, 3.33%
  3. Visual Acuity Reduced (reduced clearness of vision): 1 person, 3.33%
  4. Vision Blurred: 1 person, 3.33%
  5. Nearsightedness (difficulty in seeing the far objects): 1 person, 3.33%
  6. Eye Irritation: 1 person, 3.33%
  7. Corneal Oedema (corneal swelling): 1 person, 3.33%
  8. Conjunctival Oedema (conjunctival swelling): 1 person, 3.33%
  9. Choroidal Detachment (separation of vascular layer of the eye): 1 person, 3.33%

What are the existing conditions these people have? *

  1. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 10.00%
  2. Affective Disorder (mental disorder): 2 people, 6.67%
  3. Weight Loss: 1 person, 3.33%
  4. Weight Decreased: 1 person, 3.33%
  5. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 3.33%
  6. High Blood Pressure: 1 person, 3.33%
  7. Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 3.33%
  8. Asthma: 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Olanzapine and have Angle closure glaucoma?

- Check whether Angle closure glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Olanzapine:

Angle closure glaucoma treatments and more:

How severe was Angle closure glaucoma and when was it recovered:

Expand to all the drugs that have ingredients of olanzapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Olanzapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angle closure glaucoma:

Browse all the conditions that are associated with Angle closure glaucoma:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on olanzapine (the active ingredients of Olanzapine) and Olanzapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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