Oncaspar and Heart rate increased - a phase IV clinical study of FDA data

Summary:

Heart rate increased is reported as a side effect among people who take Oncaspar (pegaspargase), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Methotrexate, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Heart rate increased when taking Oncaspar. It is created by eHealthMe based on reports of 5,503 people who have side effects when taking Oncaspar from the FDA, and is updated regularly.

What is Oncaspar?

Oncaspar has active ingredients of pegaspargase. eHealthMe is studying from 5,504 Oncaspar users. Check the latest studies of Oncaspar.

What is Heart rate increased?

Heart rate increased is found to be associated with 2,387 drugs and 3,212 conditions by eHealthMe. Check the latest studies of Heart rate increased.

On Jun, 01, 2026

5,503 people reported to have side effects when taking Oncaspar.
Among them, 59 people (1.07%) have Heart rate increased.

Could Oncaspar cause Heart rate increased?

Among these 59 people:

How long have people been on Oncaspar when they have Heart rate increased? *

What is the gender of people who have Heart rate increased when taking Oncaspar? *

female: 49.12 %
male: 50.88 %

What is the age of people who have Heart rate increased when taking Oncaspar? *

What are other drugs people take besides Oncaspar? *

What are other side effects people have besides Heart rate increased? *

Hypotension (abnormally low blood pressure): 27 people, 45.76%
Nausea And Vomiting: 15 people, 25.42%
Fever: 14 people, 23.73%
Dyspnea (difficult or laboured breathing): 12 people, 20.34%
Nausea (feeling of having an urge to vomit): 12 people, 20.34%
Abdominal Pain: 11 people, 18.64%
Weakness: 10 people, 16.95%
Febrile Neutropenia (fever with reduced white blood cells): 10 people, 16.95%
Fatigue (feeling of tiredness): 9 people, 15.25%
Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 13.56%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 3.39%
Precursor B-Lymphoblastic Lymphoma (precursor b-cell cancer): 1 person, 1.69%
Burkitt Lymphoma (cancer of the lymphatic system): 1 person, 1.69%

* Approximation only. Some reports may have incomplete information.

Do you take Oncaspar and have Heart rate increased?

- Check whether Heart rate increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oncaspar:

Oncaspar (5,504 reports)

Browse all side effects of Oncaspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart rate increased:

Heart rate increased (2,387 drugs)

Browse all the conditions that are associated with Heart rate increased:

Heart rate increased (3,212 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pegaspargase (the active ingredients of Oncaspar) and Oncaspar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.