Oncaspar and Pupil fixed - a phase IV clinical study of FDA data

Summary:

Pupil fixed is reported as a side effect among people who take Oncaspar (pegaspargase), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Methotrexate, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Pupil fixed when taking Oncaspar. It is created by eHealthMe based on reports of 5,503 people who have side effects when taking Oncaspar from the FDA, and is updated regularly.

What is Oncaspar?

Oncaspar has active ingredients of pegaspargase. eHealthMe is studying from 5,504 Oncaspar users. Check the latest studies of Oncaspar.

What is Pupil fixed?

Pupil fixed is found to be associated with 296 drugs and 498 conditions by eHealthMe. Check the latest studies of Pupil fixed.

On Jul, 19, 2026

5,503 people reported to have side effects when taking Oncaspar.
Among them, 14 people (0.25%) have Pupil fixed.

Among these 14 people:

How long have people been on Oncaspar when they have Pupil fixed? *

What is the gender of people who have Pupil fixed when taking Oncaspar? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Pupil fixed when taking Oncaspar? *

What are other drugs people take besides Oncaspar? *

What are other side effects people have besides Pupil fixed? *

Unresponsive To Stimuli: 5 people, 35.71%
Hypotension (abnormally low blood pressure): 4 people, 28.57%
Cerebral Haemorrhage (bleeding within the brain): 4 people, 28.57%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 28.57%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 3 people, 21.43%
Bradycardia (abnormally slow heart action): 3 people, 21.43%
Weakness: 3 people, 21.43%
Brain Herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull): 3 people, 21.43%
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery): 3 people, 21.43%
Arrhythmias (irregular heartbeat): 3 people, 21.43%

What are the existing conditions these people have? *

T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 1 person, 7.14%
B Precursor Type Acute Leukaemia (lymphoid cancer): 1 person, 7.14%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Oncaspar and have Pupil fixed?

- Check whether Pupil fixed is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oncaspar:

Oncaspar (5,504 reports)

Pupil fixed treatments and more:

Pupil fixed (2,644 reports)

Browse all side effects of Oncaspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pupil fixed:

Pupil fixed (296 drugs)

Browse all the conditions that are associated with Pupil fixed:

Pupil fixed (498 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pegaspargase (the active ingredients of Oncaspar) and Oncaspar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.