Oncovin and Splenomegaly - a phase IV clinical study of FDA data

Summary:

Splenomegaly is reported as a side effect among people who take Oncovin (vincristine sulfate), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Cyclophosphamide, and have Non-hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Splenomegaly when taking Oncovin. It is created by eHealthMe based on reports of 6,660 people who have side effects when taking Oncovin from the FDA, and is updated regularly.

What is Oncovin?

Oncovin has active ingredients of vincristine sulfate. eHealthMe is studying from 6,667 Oncovin users. Check the latest studies of Oncovin.

What is Splenomegaly?

Splenomegaly (enlargement of spleen) is found to be associated with 1,114 drugs and 1,477 conditions by eHealthMe. Check the latest studies of Splenomegaly.



On Jul, 14, 2026

6,660 people reported to have side effects when taking Oncovin.
Among them, 25 people (0.38%) have Splenomegaly.

Could Oncovin cause Splenomegaly?

Among these 25 people:

How long have people been on Oncovin when they have Splenomegaly? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Splenomegaly when taking Oncovin? *

  • female: 36 %
  • male: 64 %

What is the age of people who have Splenomegaly when taking Oncovin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 13.64 %
  • 20-29: 0.0 %
  • 30-39: 13.64 %
  • 40-49: 0.0 %
  • 50-59: 13.64 %
  • 60+: 59.09 %

What are other drugs people take besides Oncovin? *

  1. Cyclophosphamide: 8 people, 32.00%
  2. Prednisolone: 7 people, 28.00%
  3. Rituxan: 5 people, 20.00%
  4. Prednisone: 5 people, 20.00%
  5. Decadron: 4 people, 16.00%
  6. Lasix: 4 people, 16.00%
  7. Alkeran: 4 people, 16.00%
  8. Fluconazole: 2 people, 8.00%
  9. Tylenol: 2 people, 8.00%
  10. Adriamycin Pfs: 2 people, 8.00%

What are other side effects people have besides Splenomegaly? *

  1. Blood Bilirubin Increased: 7 people, 28.00%
  2. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 5 people, 20.00%
  3. Hepatic Function Abnormal: 5 people, 20.00%
  4. Nausea (feeling of having an urge to vomit): 4 people, 16.00%
  5. Thrombocytopenia (decrease of platelets in blood): 4 people, 16.00%
  6. Dyspnea Exertional: 4 people, 16.00%
  7. Electrocardiogram Abnormal: 4 people, 16.00%
  8. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 16.00%
  9. Haemoglobin Decreased: 4 people, 16.00%
  10. Pulmonary Vein Occlusion (blockage in pulmonary vein): 4 people, 16.00%

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 16.00%
  2. Drug Abuse: 3 people, 12.00%
  3. Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 3 people, 12.00%
  4. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 12.00%
  5. Upper Respiratory Tract Infection: 1 person, 4.00%
  6. T-Cell Depletion (less supply of t-cell by bone marrow): 1 person, 4.00%
  7. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 4.00%
  8. Graft Versus Host Disease In Liver (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the liver): 1 person, 4.00%
  9. Angioimmunoblastic T-Cell Lymphoma (mature t-cell cancer of the blood or lymph vessel): 1 person, 4.00%
  10. Abdominal Neoplasm (cancer of the stomach): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oncovin and have Splenomegaly?

- Check whether Splenomegaly is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oncovin:

Splenomegaly treatments and more:

How severe was Splenomegaly and when was it recovered:

Expand to all the drugs that have ingredients of vincristine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oncovin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Splenomegaly:

Browse all the conditions that are associated with Splenomegaly:


How the study uses the data?

The study uses data from the FDA. It is based on vincristine sulfate (the active ingredients of Oncovin) and Oncovin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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