Onfi and Screaming - a phase IV clinical study of FDA data

Summary:

Screaming is reported as a side effect among people who take Onfi (clobazam), especially for people who are male, 30-39 old, also take Epidiolex, and have Lennox-gastaut syndrome.

The phase IV clinical study analyzes which people have Screaming when taking Onfi. It is created by eHealthMe based on reports of 7,698 people who have side effects when taking Onfi from the FDA, and is updated regularly.

What is Onfi?

Onfi has active ingredients of clobazam. It is often used in epilepsy. eHealthMe is studying from 7,809 Onfi users. Check the latest studies of Onfi.

What is Screaming?

Screaming (a long loud piercing cry) is found to be associated with 556 drugs and 775 conditions by eHealthMe. Check the latest studies of Screaming.

On Jul, 19, 2026

7,698 people reported to have side effects when taking Onfi.
Among them, 28 people (0.36%) have Screaming.

Among these 28 people:

What is the gender of people who have Screaming when taking Onfi? *

female: 35.29 %
male: 64.71 %

What is the age of people who have Screaming when taking Onfi? *

What are other drugs people take besides Onfi? *

What are other side effects people have besides Screaming? *

Insomnia (sleeplessness): 7 people, 25.00%
Fatigue (feeling of tiredness): 5 people, 17.86%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 14.29%
Abnormal Behavior: 4 people, 14.29%
Aggression: 4 people, 14.29%
Agitation (state of anxiety or nervous excitement): 4 people, 14.29%
Crying: 4 people, 14.29%
Anger: 4 people, 14.29%
Irritability: 3 people, 10.71%
Mania (a state of abnormally elevated or irritable mood): 3 people, 10.71%

What are the existing conditions these people have? *

Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 4 people, 14.29%
Infantile Spasms: 3 people, 10.71%
Sleep Disorder: 2 people, 7.14%
Headache (pain in head): 2 people, 7.14%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 7.14%
Stress And Anxiety: 1 person, 3.57%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 1 person, 3.57%
Quadriplegia (a four limb paralysis): 1 person, 3.57%
Movement - Uncontrolled Or Slow: 1 person, 3.57%
Itching: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Onfi and have Screaming?

- Check whether Screaming is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Onfi:

Onfi (7,809 reports)

Screaming treatments and more:

Screaming (7,292 reports)

Browse all side effects of Onfi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Screaming:

Screaming (556 drugs)

Browse all the conditions that are associated with Screaming:

Screaming (775 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on clobazam (the active ingredients of Onfi) and Onfi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.