Onivyde and Dehydration - a phase IV clinical study of FDA data

Summary:

Dehydration is reported as a side effect among people who take Onivyde (irinotecan hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Fluorouracil, and have Pancreatic carcinoma metastatic.

The phase IV clinical study analyzes which people have Dehydration when taking Onivyde. It is created by eHealthMe based on reports of 1,198 people who have side effects when taking Onivyde from the FDA, and is updated regularly.

What is Onivyde?

Onivyde has active ingredients of irinotecan hydrochloride. eHealthMe is studying from 1,198 Onivyde users. Check the latest studies of Onivyde.

What is Dehydration?

Dehydration (dryness resulting from the removal of water) is found to be associated with 2,753 drugs and 3,349 conditions by eHealthMe. Check the latest studies of Dehydration.



On Jul, 15, 2026

1,198 people reported to have side effects when taking Onivyde.
Among them, 17 people (1.42%) have Dehydration.

Could Onivyde cause Dehydration?

Among these 17 people:

How long have people been on Onivyde when they have Dehydration? *

  • < 1 month: 83.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 16.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Dehydration when taking Onivyde? *

  • female: 43.75 %
  • male: 56.25 %

What is the age of people who have Dehydration when taking Onivyde? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 6.67 %
  • 60+: 93.33 %

What are other drugs people take besides Onivyde? *

  1. Fluorouracil: 9 people, 52.94%
  2. Leucovorin Calcium: 3 people, 17.65%
  3. Lomotil: 2 people, 11.76%
  4. Oxaliplatin: 2 people, 11.76%
  5. Creon: 2 people, 11.76%
  6. Dexamethasone: 1 person, 5.88%
  7. Hydrochlorothiazide: 1 person, 5.88%
  8. Folic Acid: 1 person, 5.88%
  9. Finasteride: 1 person, 5.88%
  10. Zopiclone: 1 person, 5.88%

What are other side effects people have besides Dehydration? *

  1. Diarrhea: 12 people, 70.59%
  2. Weakness: 9 people, 52.94%
  3. Fatigue (feeling of tiredness): 8 people, 47.06%
  4. Nausea (feeling of having an urge to vomit): 8 people, 47.06%
  5. Abdominal Pain: 6 people, 35.29%
  6. Nausea And Vomiting: 6 people, 35.29%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 29.41%
  8. General Physical Health Deterioration (weak health status): 5 people, 29.41%
  9. Weight Decreased: 5 people, 29.41%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 17.65%

What are the existing conditions these people have? *

  1. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 6 people, 35.29%
  2. Pancreatic Carcinoma (pancreatic cancer): 4 people, 23.53%
  3. Oesophageal Carcinoma (cancer tumour of oesophagus): 2 people, 11.76%
  4. Oesophageal Cancer Metastatic (cancer of oesophagues spreads to other part): 1 person, 5.88%
  5. Nausea (feeling of having an urge to vomit): 1 person, 5.88%
  6. Insomnia (sleeplessness): 1 person, 5.88%
  7. Hypersensitivity Pneumonitis: 1 person, 5.88%
  8. High Blood Pressure: 1 person, 5.88%
  9. Gout (uric acid crystals building up in the body): 1 person, 5.88%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Onivyde and have Dehydration?

- Check whether Dehydration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Onivyde:

Dehydration treatments and more:

How severe was Dehydration and when was it recovered:

Expand to all the drugs that have ingredients of irinotecan hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Onivyde:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dehydration:

Browse all the conditions that are associated with Dehydration:


How the study uses the data?

The study uses data from the FDA. It is based on irinotecan hydrochloride (the active ingredients of Onivyde) and Onivyde (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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