Opdivo and Left ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Left ventricular dysfunction is reported as a side effect among people who take Opdivo (nivolumab), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Keytruda, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Left ventricular dysfunction when taking Opdivo. It is created by eHealthMe based on reports of 56,294 people who have side effects when taking Opdivo from the FDA, and is updated regularly.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.

What is Left ventricular dysfunction?

Left ventricular dysfunction is found to be associated with 913 drugs and 792 conditions by eHealthMe. Check the latest studies of Left ventricular dysfunction.

On Feb, 21, 2026

56,294 people reported to have side effects when taking Opdivo.
Among them, 13 people (0.02%) have Left ventricular dysfunction.

Could Opdivo cause Left ventricular dysfunction?

Among these 13 people:

How long have people been on Opdivo when they have Left ventricular dysfunction? *

What is the gender of people who have Left ventricular dysfunction when taking Opdivo? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Left ventricular dysfunction when taking Opdivo? *

What are other drugs people take besides Opdivo? *

Paracetamol: 2 people, 15.38%
Movicol: 2 people, 15.38%
Keytruda: 2 people, 15.38%
Zopiclone: 1 person, 7.69%

What are other side effects people have besides Left ventricular dysfunction? *

Pneumonia: 3 people, 23.08%
Myocarditis (inflammation of heart muscle myocardium): 3 people, 23.08%
Congestive Cardiomyopathy (weakening of heart muscle): 3 people, 23.08%
Cardiac Failure: 3 people, 23.08%
Troponin Increased: 2 people, 15.38%
Ejection Fraction Decreased (systolic heart failure): 2 people, 15.38%
Cardiomyopathy (weakening of the heart muscle): 2 people, 15.38%
Acute Pulmonary Oedema (sudden deposit of fluid in the lung)): 2 people, 15.38%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 7.69%
Oedema Peripheral (superficial swelling): 1 person, 7.69%

What are the existing conditions these people have? *

Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 23.08%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 23.08%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 15.38%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 15.38%
Stress And Anxiety: 1 person, 7.69%
Pain: 1 person, 7.69%
Dyslipidaemia (abnormal amount of lipids): 1 person, 7.69%
Constipation: 1 person, 7.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
Bronchial Carcinoma (lung cancer): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Opdivo and have Left ventricular dysfunction?

- Check whether Left ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Opdivo:

Opdivo (56,331 reports)

Browse all side effects of Opdivo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (913 drugs)

Browse all the conditions that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (792 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nivolumab (the active ingredients of Opdivo) and Opdivo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.