Opdivo and Neutrophil count increased - a phase IV clinical study of FDA data

Summary:

Neutrophil count increased is reported as a side effect among people who take Opdivo (nivolumab), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Votrient, and have Metastatic renal cell carcinoma.

The phase IV clinical study analyzes which people have Neutrophil count increased when taking Opdivo. It is created by eHealthMe based on reports of 56,294 people who have side effects when taking Opdivo from the FDA, and is updated regularly.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.

What is Neutrophil count increased?

Neutrophil count increased (excess than normal number of neutrophil a type of blood cell) is found to be associated with 942 drugs and 1,170 conditions by eHealthMe. Check the latest studies of Neutrophil count increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

56,294 people reported to have side effects when taking Opdivo.
Among them, 14 people (0.02%) have Neutrophil count increased.

Could Opdivo cause Neutrophil count increased?

Among these 14 people:

How long have people been on Opdivo when they have Neutrophil count increased? *

What is the gender of people who have Neutrophil count increased when taking Opdivo? *

female: 50 %
male: 50 %

What is the age of people who have Neutrophil count increased when taking Opdivo? *

What are other drugs people take besides Opdivo? *

What are other side effects people have besides Neutrophil count increased? *

High Blood Pressure: 6 people, 42.86%
Nausea And Vomiting: 5 people, 35.71%
Malignant Neoplasm Progression (cancer tumour came back): 5 people, 35.71%
Haemoglobin Decreased: 4 people, 28.57%
Anaemia (lack of blood): 4 people, 28.57%
Rashes (redness): 4 people, 28.57%
Abdominal Pain Lower: 3 people, 21.43%
General Physical Health Deterioration (weak health status): 3 people, 21.43%
Gamma-Glutamyltransferase Increased: 3 people, 21.43%
Flatulence (flatus expelled through the anus): 3 people, 21.43%

What are the existing conditions these people have? *

Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 35.71%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 21.43%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 21.43%
High Blood Pressure: 3 people, 21.43%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 21.43%
Chondrosarcoma (common form of bone cancer): 3 people, 21.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 21.43%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 14.29%
Oral Cancer (mouth cancer): 2 people, 14.29%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Opdivo and have Neutrophil count increased?

- Check whether Neutrophil count increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Opdivo:

Opdivo (56,331 reports)

Browse all side effects of Opdivo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neutrophil count increased:

Neutrophil count increased (942 drugs)

Browse all the conditions that are associated with Neutrophil count increased:

Neutrophil count increased (1,170 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nivolumab (the active ingredients of Opdivo) and Opdivo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.