Opdivo and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Opdivo (nivolumab), especially for people who are male, 60+ old, also take Gravol, and have Carcinoid tumor.

The phase IV clinical study analyzes which people have Sciatica when taking Opdivo. It is created by eHealthMe based on reports of 56,294 people who have side effects when taking Opdivo from the FDA, and is updated regularly.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,143 drugs and 1,433 conditions by eHealthMe. Check the latest studies of Sciatica.

On Jun, 20, 2026

56,294 people reported to have side effects when taking Opdivo.
Among them, 15 people (0.03%) have Sciatica.

Among these 15 people:

What is the gender of people who have Sciatica when taking Opdivo? *

female: 20 %
male: 80 %

What is the age of people who have Sciatica when taking Opdivo? *

What are other drugs people take besides Opdivo? *

What are other side effects people have besides Sciatica? *

Diarrhea: 7 people, 46.67%
Malignant Neoplasm Progression (cancer tumour came back): 7 people, 46.67%
Back Pain: 6 people, 40.00%
Nausea (feeling of having an urge to vomit): 6 people, 40.00%
Weight Decreased: 5 people, 33.33%
Heart Rate Increased: 5 people, 33.33%
Metastases To Kidney (cancer spreads to kidney): 5 people, 33.33%
Joint Swelling: 5 people, 33.33%
High Blood Pressure: 5 people, 33.33%
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 5 people, 33.33%

What are the existing conditions these people have? *

Carcinoid Tumor: 5 people, 33.33%
Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 26.67%
Renal Cell Carcinoma (a kidney cancer): 2 people, 13.33%
Pain: 2 people, 13.33%
Hodgkin's Lymphoma (cancer originating from white blood cells): 2 people, 13.33%
Diarrhea: 2 people, 13.33%
Colitis (inflammation of colon): 2 people, 13.33%
Renal Cancer Stage I (the tumour is 7 cm or smaller and is in the kidney only. it has not spread to the lymph nodes): 1 person, 6.67%
Malignant Melanoma (skin cancer rises from melancytes): 1 person, 6.67%
Colon Cancer: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Opdivo and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Opdivo:

Opdivo (56,331 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

Browse all side effects of Opdivo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,143 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,433 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nivolumab (the active ingredients of Opdivo) and Opdivo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.