Opsumit and Panic attacks - a phase IV clinical study of FDA data

Summary:

Panic attacks is reported as a side effect among people who take Opsumit (macitentan), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Adempas, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Panic attacks when taking Opsumit. It is created by eHealthMe based on reports of 67,913 people who have side effects when taking Opsumit from the FDA, and is updated regularly.

What is Opsumit?

Opsumit has active ingredients of macitentan. eHealthMe is studying from 67,926 Opsumit users. Check the latest studies of Opsumit.

What is Panic attacks?

Panic attacks is found to be associated with 2,300 drugs and 2,078 conditions by eHealthMe. Check the latest studies of Panic attacks.

On Apr, 24, 2026

67,913 people reported to have side effects when taking Opsumit.
Among them, 159 people (0.23%) have Panic attacks.

Among these 159 people:

How long have people been on Opsumit when they have Panic attacks? *

What is the gender of people who have Panic attacks when taking Opsumit? *

female: 92.99 %
male: 7.01 %

What is the age of people who have Panic attacks when taking Opsumit? *

What are other drugs people take besides Opsumit? *

What are other side effects people have besides Panic attacks? *

Dyspnea (difficult or laboured breathing): 101 people, 63.52%
Stress And Anxiety: 77 people, 48.43%
Fatigue (feeling of tiredness): 68 people, 42.77%
Headache (pain in head): 66 people, 41.51%
Dyspnea Exertional: 49 people, 30.82%
Cough: 48 people, 30.19%
Chest Pain: 46 people, 28.93%
Nausea (feeling of having an urge to vomit): 42 people, 26.42%
Dizziness: 42 people, 26.42%
Malaise (a feeling of general discomfort or uneasiness): 35 people, 22.01%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 127 people, 79.87%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 21 people, 13.21%
Cardiac Failure Congestive: 7 people, 4.40%
Oedema (fluid collection in tissue): 4 people, 2.52%
Stress And Anxiety: 3 people, 1.89%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 0.63%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 0.63%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 0.63%
Dyspnea (difficult or laboured breathing): 1 person, 0.63%
Connective Tissue Disorder (any disease that has the connective tissues of the body): 1 person, 0.63%

* Approximation only. Some reports may have incomplete information.

Do you take Opsumit and have Panic attacks?

- Check whether Panic attacks is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Opsumit:

Opsumit (67,926 reports)

Panic attacks treatments and more:

Panic attacks (65,704 reports)

Browse all side effects of Opsumit:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Panic attacks:

Panic attacks (2,300 drugs)

Browse all the conditions that are associated with Panic attacks:

Panic attacks (2,078 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on macitentan (the active ingredients of Opsumit) and Opsumit (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.